3-[(E)-(Dimethylhydrazinylidene)methyl]pyridine

Base Information

• Chemical Name: 3-[(E)-(Dimethylhydrazinylidene)methyl]pyridine
• CAS No.: 59670-91-6
• Molecular Formula: C8H11N3
• Molecular Weight: 149.195
• DSSTox Substance ID: DTXSID70421526
• Mol file: 59670-91-6.mol

Synonyms:SCHEMBL7662089;DTXSID70421526;59670-91-6;3-[(E)-(Dimethylhydrazinylidene)methyl]pyridine

Chemical Property of 3-[(E)-(Dimethylhydrazinylidene)methyl]pyridine

Chemical Property:

• Vapor Pressure: 0.00417mmHg at 25°C
• Boiling Point: 278.8°Cat760mmHg
• Flash Point: 122.4°C
• Density: 0.98g/cm³
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 149.095297364
• Heavy Atom Count: 11
• Complexity: 131

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)N=CC1=CN=CC=C1
• Isomeric SMILES: CN(C)/N=C/C1=CN=CC=C1

Technology Process of 3-[(E)-(Dimethylhydrazinylidene)methyl]pyridine

There total 4 articles about 3-[(E)-(Dimethylhydrazinylidene)methyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-pyridinecarboxaldehyde (500-22-1) + N,N-Dimethylhydrazine (57-14-7) → nicotinaldehyde dimethylhydrazone (59670-91-6)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 20 ℃; for 10h;

DOI:10.1021/ol2016803

Reference yield: 77.0%

3-pyridinecarboxaldehyde (500-22-1) + N,N-Dimethylhydrazine (57-14-7) → N,N-dimethyl-N'-(pyridin-3-ylmethylene)-hydrazine (59670-91-6)

Guidance literature:

In ethanol; for 0.5h; heating on a steam bath;

DOI:10.1016/0223-5234(89)90016-0

Reference yield:

3-pyridinecarboxaldehyde (500-22-1) + dimethyl trimethylsilyl phosphite (36198-87-5) + N,N-Dimethylhydrazine (57-14-7) + isobutyraldehyde (78-84-2) → N,N-dimethyl-N'-(pyridin-3-ylmethylene)-hydrazine (59670-91-6) + [1-(N',N'-dimethyl-hydrazino)-2-methyl-propyl]-phosphonic acid dimethyl ester

Guidance literature:

With lithium perchlorate; In diethyl ether; at 20 ℃; for 1h;

DOI:10.1016/S0040-4039(01)01702-6

upstream raw materials:

3-pyridinecarboxaldehyde

N,N-Dimethylhydrazine

dimethyl trimethylsilyl phosphite

isobutyraldehyde

Downstream raw materials:

pyridine-3-carbonitrile

[2-(dimethylamino)phenyl](pyridin-3-yl)methanone