6-Amino-1-benzyl-5-methylaminouracil

Base Information

Chemical Name:6-Amino-1-benzyl-5-methylaminouracil
CAS No.:72816-88-7
Molecular Formula:C12H14N4O2
Molecular Weight:246.269
Hs Code.:2933599090
DSSTox Substance ID:DTXSID80352418
Wikidata:Q27212923
ChEMBL ID:CHEMBL1542208
Mol file:72816-88-7.mol

Synonyms:72816-88-7;6-AMINO-1-BENZYL-5-METHYLAMINOURACIL;6-amino-1-benzyl-5-(methylamino)pyrimidine-2,4-dione;6-Amino-1-benzyl-5-(methylamino)pyrimidine-2,4(1H,3H)-dione;MLS000564217;SMR000151677;6-amino-1-benzyl-5-(methylamino)-1,2,3,4-tetrahydropyrimidine-2,4-dione;6-amino-5-(methylamino)-1-(phenylmethyl)pyrimidine-2,4-dione;Oprea1_069072;cid_726225;SCHEMBL6350010;CHEMBL1542208;BDBM52313;DTXSID80352418;CHEBI:123234;HMS2406N11;AKOS000115984;SB59615;CS-0219035;FT-0661599;EN300-02890;AB-323/13887120;W-203652;Q27212923;Z55848625;6-amino-1-benzyl-5-(methylamino)pyrimidine-2,4-quinone;6-amino-1-benzyl-5-(methylamino)-2,4(1H,3H)-pyrimidinedione;6-azanyl-5-(methylamino)-1-(phenylmethyl)pyrimidine-2,4-dione;6-Amino-1-benzyl-5-methylamino-1H-pyrimidine-2,4-dione, AldrichCPR;I2Z

Suppliers and Price of 6-Amino-1-benzyl-5-methylaminouracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Amino-1-benzyl-5-methylaminouracil
250mg
$ 100.00

Medical Isotopes, Inc.
6-Amino-1-benzyl-5-methylaminouracil
2.5 g
$ 1760.00

Biosynth Carbosynth
6-Amino-1-benzyl-5-methylaminouracil
500 mg
$ 160.00

Biosynth Carbosynth
6-Amino-1-benzyl-5-methylaminouracil
250 mg
$ 105.00

Biosynth Carbosynth
6-Amino-1-benzyl-5-methylaminouracil
1 g
$ 241.50

American Custom Chemicals Corporation
6-AMINO-1-BENZYL-5-METHYLAMINO-1H-PYRIMIDINE-2,4-DIONE 95.00%
5G
$ 1463.85

American Custom Chemicals Corporation
6-AMINO-1-BENZYL-5-METHYLAMINO-1H-PYRIMIDINE-2,4-DIONE 95.00%
2.5G
$ 1173.77

American Custom Chemicals Corporation
6-AMINO-1-BENZYL-5-METHYLAMINO-1H-PYRIMIDINE-2,4-DIONE 95.00%
1G
$ 823.44

AK Scientific
6-Amino-1-benzyl-5-methylaminouracil
250mg
$ 232.00

Total 8 raw suppliers

Chemical Property of 6-Amino-1-benzyl-5-methylaminouracil

Chemical Property:

Appearance/Colour:White Powder
Melting Point:217-221 ºC
Refractive Index:1.654
PSA：92.91000
Density:1.34 g/cm³
LogP:0.86300
Storage Temp.:-20°C Freezer
XLogP3:0.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:246.11167570
Heavy Atom Count:18
Complexity:386

Purity/Quality:

99% ^*data from raw suppliers

6-Amino-1-benzyl-5-methylaminouracil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C(N(C(=O)NC1=O)CC2=CC=CC=C2)N

Technology Process of 6-Amino-1-benzyl-5-methylaminouracil

There total 4 articles about 6-Amino-1-benzyl-5-methylaminouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 41862-11-7
1-benzyl-6-aminouracil

: 74-89-5
methylamine

: 72816-88-7
6-amino-1-benzyl-5-N-methylaminouracil

Guidance literature:: 1-benzyl-6-aminouracil; With bromine; sodium hydrogencarbonate; In methanol; at 0 - 20 ℃; for 0.5h;

methylamine; In methanol; water; at 70 ℃; for 4h;
DOI:10.1021/cb300426u

Reference yield:

: 72816-87-6
6-amino-1-benzyl-5-bromo-2,4(1H)-pyrimidinedione

: 74-89-5
methylamine

: 72816-88-7
6-amino-1-benzyl-5-N-methylaminouracil

Guidance literature:: In water; at 70 ℃; for 4h;
DOI:10.1021/jm011093d

Reference yield:

: 538-32-9
benzylurea

: 72816-88-7
6-amino-1-benzyl-5-N-methylaminouracil

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic anhydride / 2 h / 80 °C

1.2: 1 h / 85 °C

2.1: sodium hydrogencarbonate; bromine / methanol / 0.5 h / 0 - 20 °C

2.2: 4 h / 70 °C

With bromine; acetic anhydride; sodium hydrogencarbonate; In methanol;
DOI:10.1021/cb300426u