Bis(4-methoxyphenyl)phosphine

Base Information

• Chemical Name: Bis(4-methoxyphenyl)phosphine
• CAS No.: 84127-04-8
• Molecular Formula: C14H15O2P
• Molecular Weight: 246.246
• Hs Code.: 2931900090
• Mol file: 84127-04-8.mol

Synonyms:Bis(4-methoxyphenyl)phosphine

Chemical Property of Bis(4-methoxyphenyl)phosphine

Chemical Property:

• Melting Point: 36-40°C
• Boiling Point: 352.4±42.0 °C(Predicted)
• Flash Point: >110℃
• PSA: 32.05000
• LogP: 2.33310

Purity/Quality:

98% ^*data from raw suppliers

Bis(4-methoxyphenyl)phosphine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 11-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Reactant for:Enantioselective Ir-catalyzed hydrogenationPalladium-catalyzed asymmetric additionsAlkali-metal-catalyzed addition reactionsPreparation of different DIOP-type ligands for uses in Rh-catalyzed asymmetric hydrogenation

Technology Process of Bis(4-methoxyphenyl)phosphine

There total 20 articles about Bis(4-methoxyphenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

bis(4-methoxyphenyl)phosphine oxide (15754-51-5) → bis(4-methoxyphenyl)phosphine (84127-04-8)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; at 25 ℃; for 0.666667h;

DOI:10.1021/ol0517832

Reference yield: 91.0%

→ bis(4-methoxyphenyl)phosphine (84127-04-8)

Guidance literature:

Reference yield: 81.0%

bis(4-methoxyphenyl)phosphine-borane complex + ethanol (64-17-5) → triethyl borate (150-46-9) + bis(4-methoxyphenyl)phosphine (84127-04-8)

Guidance literature:

Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2009.05.063

upstream raw materials:

chlorobis(4-methoxyphenyl)phosphane

bis(4-methoxyphenyl)phenylphosphine

P(p-CH₃OC₆H₄)3

Bis-(4-methoxy-phenyl)-(2-methoxy-phenyl)-phosphane

Downstream raw materials:

(R,R)-4,5-Bis-2,2-dimethyl-1,3-dioxolan

<(2S)-3-methyl-2-(methylsulfonylamino)butyl>bis(4-methoxyphenyl)phosphine

(4R,5R)-4-bis(4-methoxyphenyl)phosphinomethyl-5-bis(4-trimethylsilylphenyl)phosphinomethyl-2,2-dimethyl-1,3-dioxolane

C₂₇H₂₆NO₄P

Refernces

• 1、 Kang, Qi-Kai,Li, Yuntong,Lin, Yunzhi,Shi, Hang. "Ru(II)-Catalyzed Amination of Aryl Fluorides via η6-Coordination". supporting information. p. 3706 - 3711. Retrieved 2020/03/11.
• 2、 Liu, Weiping,Sahoo, Basudev,Spannenberg, Anke,Junge, Kathrin,Beller, Matthias. "Tailored Cobalt-Catalysts for Reductive Alkylation of Anilines with Carboxylic Acids under Mild Conditions". supporting information. p. 11673 - 11677. Retrieved 2018/09/10.