Ethyl 4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate

Base Information

Chemical Name:Ethyl 4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate
CAS No.:148858-09-7
Molecular Formula:C13H13N3O2
Molecular Weight:243.26
Hs Code.:
Mol file:148858-09-7.mol

Synonyms:Ethyl 4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate;4,5-Dihydro-Imidazo[1,5-A]Quinoxaline-3-Carboxylic Acid Ethyl Ester

Suppliers and Price of Ethyl 4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,5-Dihydro-imidazo[1,5-a]quinoxaline-3-carboxylicacidethylester
10mg
$ 265.00

Crysdot
Ethyl4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate 95+%
1g
$ 880.00

AccelPharmtech
4,5-dihydro-Imidazo[1,5-a]quinoxaline-3-carboxylicacidethylester 97.00%
1G
$ 1940.00

Total 2 raw suppliers

Chemical Property of Ethyl 4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate

Chemical Property:

PSA：56.15000
LogP:2.11250

Purity/Quality:

≥99% ^*data from raw suppliers

4,5-Dihydro-imidazo[1,5-a]quinoxaline-3-carboxylicacidethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethyl 4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate

There total 5 articles about Ethyl 4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2999-46-4
Ethyl isocyanoacetate

: 59564-59-9
1,2,3,4-tetrahydroquinoxalin-2-one

: 148858-09-7
ethyl 4,5-dihydroimidazo<1,5-a>quinoxaline-3-carboxylate

Guidance literature:: With potassium tert-butylate; diethyl chlorophosphate; Yield given. Multistep reaction; 1.) THF, a) -78 deg C, 15 min, b) from -78 deg C to RT, 45 min, 2.) THF, a) -78 deg C, 2 h, b) from -78 deg C to RT, 30 min;
DOI:10.1021/jm00032a008

Reference yield:

: 2999-46-4
Ethyl isocyanoacetate

: ammonium chloride

: 814-49-3
diethyl chlorophosphate

: 59564-59-9
1,2,3,4-tetrahydroquinoxalin-2-one

: 148858-09-7
ethyl 4,5-dihydroimidazo<1,5-a>quinoxaline-3-carboxylate

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; dichloromethane; chloroform;

Reference yield:

: 5428-05-7
n-(2-nitrophenyl)glycine ethyl ester

: 148858-09-7
ethyl 4,5-dihydroimidazo<1,5-a>quinoxaline-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / H₂ / 10percent Pd/C / methanol / 1.5 h / 1810.02 Torr

2: 1.) potassium tert-butoxide, diethyl chlorophosphate / 1.) THF, a) -78 deg C, 15 min, b) from -78 deg C to RT, 45 min, 2.) THF, a) -78 deg C, 2 h, b) from -78 deg C to RT, 30 min

With potassium tert-butylate; hydrogen; diethyl chlorophosphate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00032a008