tert-Butyl N-(trans-3-aMinocyclobutyl)-N-MethylcarbaMate

Base Information

• Chemical Name: tert-Butyl N-(trans-3-aMinocyclobutyl)-N-MethylcarbaMate
• CAS No.: 1392803-14-3
• Molecular Formula: C10H20N2O2
• Molecular Weight: 200.278
• Mol file: 1392803-14-3.mol

Synonyms:tert-Butyl N-(trans-3-aMinocyclobutyl)-N-MethylcarbaMate;trans-tert-Butyl-3-aminocyclobutyl(methyl)carbamate

Chemical Property of tert-Butyl N-(trans-3-aMinocyclobutyl)-N-MethylcarbaMate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

tert-ButylN-(trans-3-aminocyclobutyl)-N-methylcarbamate 97.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyl N-(trans-3-aMinocyclobutyl)-N-MethylcarbaMate

There total 8 articles about tert-Butyl N-(trans-3-aMinocyclobutyl)-N-MethylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (trans-3-azidocyclobutyl)methylcarbamate → tert-butyl (trans-3-aminocyclobutyl)methylcarbamate (1392803-14-3,1392803-87-0)

Guidance literature:

With palladium on activated charcoal; ammonia; hydrogen; In methanol; at 20 ℃; for 3h;

Reference yield:

cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate (1033718-11-4) → tert-butyl (trans-3-aminocyclobutyl)methylcarbamate (1392803-14-3,1392803-87-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 70 °C

2: hydrogen; palladium on activated charcoal; ammonia / methanol / 3 h / 20 °C

With sodium azide; palladium on activated charcoal; ammonia; hydrogen; In methanol; N,N-dimethyl-formamide;

Reference yield:

(3-methylene-cyclobutyl)-carbamic acid tert-butyl ester (130369-04-9) → tert-butyl (trans-3-aminocyclobutyl)methylcarbamate (1392803-14-3,1392803-87-0)

Guidance literature:

Multi-step reaction with 8 steps

1.1: ozone / methanol; dichloromethane / -78 °C / Inert atmosphere

2.1: L-Selectride / tetrahydrofuran / 2.5 h / -72 - 20 °C

3.1: pyridine / 20 °C

4.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 20 °C

4.2: 0 - 20 °C

5.1: tetrabutyl ammonium fluoride; pyridine / 2 h / 20 °C

6.1: triethylamine / dichloromethane / -30 °C

6.2: 1.17 h / 20 °C

7.1: sodium azide / N,N-dimethyl-formamide / 70 °C

8.1: hydrogen; palladium on activated charcoal; ammonia / methanol / 3 h / 20 °C

With pyridine; sodium azide; palladium on activated charcoal; tetrabutyl ammonium fluoride; ammonia; hydrogen; L-Selectride; sodium hydride; ozone; triethylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;

upstream raw materials:

cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

(3-methylene-cyclobutyl)-carbamic acid tert-butyl ester

3-(tert-butyloxycarbonylamino)cyclobutan-1-one

tert-butyl ((1s,3s)-3-hydroxycyclobutyl)carbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1392803-14-3 tert-Butyl N-(trans-3-aMinocyclobutyl)-N-MethylcarbaMate

Send

Send

Metric Ton KG G Pound L ML

Send

Send