cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

Base Information

Chemical Name:cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate
CAS No.:1033718-11-4
Molecular Formula:C₁₁H₂₁NO₅S
Molecular Weight:279.357
Hs Code.:

Synonyms:

Suppliers and Price of cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL N-METHYL-N-[(1S,3S)-3-(METHANESULFONYLOXY)CYCLOBUTYL]CARBAMATE 95.00%
5MG
$ 456.64

Total 4 raw suppliers

Chemical Property of cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

TERT-BUTYL N-METHYL-N-[(1S,3S)-3-(METHANESULFONYLOXY)CYCLOBUTYL]CARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

There total 6 articles about cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: tert-butyl (cis-3-hydroxycyclobutyl)methylcarbamate

: 124-63-0
methanesulfonyl chloride

: 1033718-11-4
cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

Guidance literature:: tert-butyl (cis-3-hydroxycyclobutyl)methylcarbamate; With triethylamine; In dichloromethane; at -30 ℃;

methanesulfonyl chloride; In dichloromethane; at 20 ℃; for 1.16667h;

Reference yield:

: 130369-04-9
(3-methylene-cyclobutyl)-carbamic acid tert-butyl ester

: 1033718-11-4
cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

Guidance literature:: Multi-step reaction with 6 steps

1.1: ozone / methanol; dichloromethane / -78 °C / Inert atmosphere

2.1: L-Selectride / tetrahydrofuran / 2.5 h / -72 - 20 °C

3.1: pyridine / 20 °C

4.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 20 °C

4.2: 0 - 20 °C

5.1: tetrabutyl ammonium fluoride; pyridine / 2 h / 20 °C

6.1: triethylamine / dichloromethane / -30 °C

6.2: 1.17 h / 20 °C

With pyridine; tetrabutyl ammonium fluoride; L-Selectride; sodium hydride; ozone; triethylamine; In tetrahydrofuran; methanol; dichloromethane; mineral oil;

Reference yield:

: 154748-49-9
3-(tert-butyloxycarbonylamino)cyclobutan-1-one

: 1033718-11-4
cis-3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutyl methanesulfonate

Guidance literature:: Multi-step reaction with 5 steps

1.1: L-Selectride / tetrahydrofuran / 2.5 h / -72 - 20 °C

2.1: pyridine / 20 °C

3.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 20 °C

3.2: 0 - 20 °C

4.1: tetrabutyl ammonium fluoride; pyridine / 2 h / 20 °C

5.1: triethylamine / dichloromethane / -30 °C

5.2: 1.17 h / 20 °C

With pyridine; tetrabutyl ammonium fluoride; L-Selectride; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; mineral oil;