1-(9-Fluorenyl)ethanol

Base Information

• Chemical Name: 1-(9-Fluorenyl)ethanol
• CAS No.: 3023-49-2
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• Hs Code.: 2906299090
• DSSTox Substance ID: DTXSID50393297
• Nikkaji Number: J642.373F
• Mol file: 3023-49-2.mol

Synonyms:3023-49-2;(+/-)-1-(9-Fluorenyl)ethanol;1-(9-FLUORENYL)ETHANOL;1-(9H-fluoren-9-yl)ethanol;|A-Methylfluorene-9-methanol;( inverted exclamation markA)-1-(9-Fluorenyl)ethanol;alpha-Methylfluorene-9-methanol;SCHEMBL2310546;DTXSID50393297;AKOS009158738;FT-0742331;E87343;J-017838;(+/-)-1-(9-Fluorenyl)ethanol, >=97.0% (HPLC)

Chemical Property of 1-(9-Fluorenyl)ethanol

Chemical Property:

• Vapor Pressure: 4.72E-06mmHg at 25°C
• Melting Point: 102-104 °C
• Boiling Point: 367.6°C at 760 mmHg
• PKA: 13.75±0.20(Predicted)
• Flash Point: 162.9°C
• PSA: 20.23000
• Density: 1.158g/cm³
• LogP: 3.17970
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 228

Purity/Quality:

98%,99%, ^*data from raw suppliers

(±)-1-(9-Fluorenyl)ethanol ≥97.0% (HPLC) ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1C2=CC=CC=C2C3=CC=CC=C13)O
• Uses: (±)-1-(9-Fluorenyl)ethanol is used as a reagent in the preparation of fluorenylethanol via enzymic kinetic resolution by transesterification using lipase.

Technology Process of 1-(9-Fluorenyl)ethanol

There total 17 articles about 1-(9-Fluorenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

9-acetylfluorene (3300-10-5) → 9-(1-hydroxyethyl)fluorene (3023-49-2,107474-78-2,151775-20-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 5 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.tetasy.2013.07.005

Reference yield: 4.9%

ethanol (64-17-5) + 9-diazofluorenone (832-80-4) → 9-(1-hydroxyethyl)fluorene (3023-49-2,107474-78-2,151775-20-1) + 9-ethoxy-fluorenes (2868-70-4)

Guidance literature:

at -196.1 ℃; for 1.25h; Product distribution; Irradiation; further light intesity, reaction time;

DOI:10.1021/ja00284a049

Reference yield:

1-(9H-fluoren-9-yl)ethyl acetate (63839-88-3) + sodium methylate (124-41-4) → acetic acid methyl ester (79-20-9) + 9-(1-hydroxyethyl)fluorene (3023-49-2,107474-78-2,151775-20-1)

Guidance literature:

In methanol; at 25 ℃; Rate constant;

upstream raw materials:

9-ethylfluorene

9-acetylfluorene

fluoren-9-ylmagnesium bromide

acetaldehyde

Downstream raw materials:

9-methylphenanthrene

9-ethylidenefluorene

9-<1-<(4'-methylbenzyl)sulfonyl>ethyl>fluorene

(1R)-(+)-1-(9H-fluoren-9-yl)ethyl acetate