Methyl 6-methylbenzofuran-2-carboxylate

Base Information

• Chemical Name: Methyl 6-methylbenzofuran-2-carboxylate
• CAS No.: 82788-37-2
• Molecular Formula: C₁₁H₁₀O₃
• Molecular Weight: 190.199
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID30546103
• Nikkaji Number: J2.251.486E
• Wikidata: Q82423809
• Mol file: 82788-37-2.mol

Synonyms:Methyl 6-methylbenzofuran-2-carboxylate;82788-37-2;Methyl 6-methyl-1-benzofuran-2-carboxylate;2-Benzofurancarboxylic acid, 6-methyl-, methyl ester;Methyl6-methylbenzofuran-2-carboxylate;SCHEMBL10955059;DTXSID30546103;KLKMCBYWDLAIBA-UHFFFAOYSA-N;MFCD11975072;AKOS016013722;DS-17089;CS-0043039;C76650;EN300-748940

Chemical Property of Methyl 6-methylbenzofuran-2-carboxylate

Chemical Property:

• PSA: 39.44000
• LogP: 2.52780
• Storage Temp.: 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 190.062994177
• Heavy Atom Count: 14
• Complexity: 227

Purity/Quality:

97% ^*data from raw suppliers

Methyl6-methylbenzofuran-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC2=C(C=C1)C=C(O2)C(=O)OC

Technology Process of Methyl 6-methylbenzofuran-2-carboxylate

There total 5 articles about Methyl 6-methylbenzofuran-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 6-methylbenzofuran-2-carboxylic acid (50779-65-2) → methyl 6-methylbenzofuran-2-carboxylate (82788-37-2)

Guidance literature:

With hydrogenchloride;

Reference yield:

6-methylbenzofuran-2-carboxylic acid (50779-65-2) + (diazomethyl)-trimethylsilane → methyl 6-methylbenzofuran-2-carboxylate (82788-37-2)

Guidance literature:

In methanol; toluene; at 20 ℃; for 6h;

Reference yield:

4-methylsalicylaldehyde (698-27-1) → methyl 6-methylbenzofuran-2-carboxylate (82788-37-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; butanone / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge

2: hydrogen chloride

With hydrogenchloride; potassium carbonate; butanone;

upstream raw materials:

methanol

6-methylbenzofuran-2-carboxylic acid

methyl 5-nitrofuran-2-carboxylate

isoprene