Technology Process of 1-(2-(2-bromoethoxy)-4-nitrophenyl)-3-methyl-1H-1,2,4-triazole
There total 5 articles about 1-(2-(2-bromoethoxy)-4-nitrophenyl)-3-methyl-1H-1,2,4-triazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
acetonitrile;
at 20 ℃;
for 18h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: boron tribromide / dichloromethane / -78 - 4 °C / Inert atmosphere
2: potassium carbonate / acetonitrile / 18 h / 20 °C
3: potassium hydroxide / dimethyl sulfoxide / 18 h / 95 °C
4: trifluoroacetic acid / dichloromethane / 1 h / 20 °C
5: potassium carbonate / acetonitrile / 18 h / 20 °C
With
boron tribromide; potassium carbonate; trifluoroacetic acid; potassium hydroxide;
In
dichloromethane; dimethyl sulfoxide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / acetonitrile / 18 h / 20 °C
2: potassium hydroxide / dimethyl sulfoxide / 18 h / 95 °C
3: trifluoroacetic acid / dichloromethane / 1 h / 20 °C
4: potassium carbonate / acetonitrile / 18 h / 20 °C
With
potassium carbonate; trifluoroacetic acid; potassium hydroxide;
In
dichloromethane; dimethyl sulfoxide; acetonitrile;
