Technology Process of 1-Benzyl-2,4-diphenyl-1H-pyrrole
There total 3 articles about 1-Benzyl-2,4-diphenyl-1H-pyrrole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: titanium(IV) tetraethanolate / n-heptane / Dean-Stark; Heating
2: palladium diacetate; tetrabutylammomium bromide; oxygen; Trimethylacetic acid / dimethyl sulfoxide / 24 h / 80 °C / Schlenk technique; Molecular sieve
With
titanium(IV) tetraethanolate; tetrabutylammomium bromide; oxygen; palladium diacetate; Trimethylacetic acid;
In
n-heptane; dimethyl sulfoxide;
DOI:10.1016/j.tetlet.2020.151887
- Guidance literature:
-
Multi-step reaction with 3 steps
2: potassium hydroxide / tetrahydrofuran; methanol; water / 36 h / 50 °C
3: trifluoroacetic anhydride / dichloromethane / 20 h / 20 °C
With
trifluoroacetic anhydride; potassium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water;
1: |Paal-Knorr Pyrrole Synthesis / 3: |Friedel-Crafts Acylation;
DOI:10.5012/bkcs.2013.34.9.2604
- Guidance literature:
-
Multi-step reaction with 3 steps
2: potassium hydroxide / tetrahydrofuran; methanol; water / 36 h / 50 °C
3: trifluoroacetic anhydride / dichloromethane / 20 h / 20 °C
With
trifluoroacetic anhydride; potassium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water;
1: |Paal-Knorr Pyrrole Synthesis / 3: |Friedel-Crafts Acylation;
DOI:10.5012/bkcs.2013.34.9.2604
