5-Bromo-2,3-dichlorothiophene

Base Information

• Chemical Name: 5-Bromo-2,3-dichlorothiophene
• CAS No.: 83663-36-9
• Molecular Formula: C4HBrCl2S
• Molecular Weight: 231.928
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID20510010
• Wikidata: Q82368006
• Mol file: 83663-36-9.mol

Synonyms:5-Bromo-2,3-dichlorothiophene;83663-36-9;SCHEMBL23531761;DTXSID20510010;MFCD23135682;AKOS016002592;AS-76947;CS-0157907;EN300-139091

Chemical Property of 5-Bromo-2,3-dichlorothiophene

Chemical Property:

• PSA: 28.24000
• LogP: 3.81740
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 229.83594
• Heavy Atom Count: 8
• Complexity: 90.1

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2,3-dichlorothiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(SC(=C1Cl)Cl)Br
• Uses: 5-Bromo-2,3-dichlorothiophene is a useful synthetic intermediate.

Technology Process of 5-Bromo-2,3-dichlorothiophene

There total 1 articles about 5-Bromo-2,3-dichlorothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.98%

2,3-Dichlorothiophene (17249-79-5) → 5-bromo-2,3-dichlorothiophene (83663-36-9)

Guidance literature:

With bromine; In dichloromethane; at 0 - 20 ℃;

Reference yield:

5-bromo-2,3-dichlorothiophene (83663-36-9) + chloroacetyl chloride (79-04-9) → 2,3-Dichlor-5-chloracetyl-thiophen (64218-50-4) + 2-Bromo-3-chloroacetyl-4,5-dichlorothiophene (83663-37-0)

Guidance literature:

With aluminium trichloride; In carbon disulfide; Yield given; 1) Room temperature, overnight, 2) reflux 1 h.;

upstream raw materials:

2,3-Dichlorothiophene

Downstream raw materials:

2,3-Dichlor-5-chloracetyl-thiophen

2-Bromo-3-chloroacetyl-4,5-dichlorothiophene