Mocetinostat hydrobromide

Base Information

Chemical Name:Mocetinostat hydrobromide
CAS No.:944537-89-7
Molecular Formula:2BrH*C₂₃H₂₀N₆O
Molecular Weight:558.275
Hs Code.:
Mol file:944537-89-7.mol

Synonyms:Mocetinostat hydrobromide;N-(2-Aminophenyl)-4-[4-(3-pyridyl)pyrimidin-2-ylaminomethyl]benzamide dihydrobromide;Mocetinostat dihydrobromide

Suppliers and Price of Mocetinostat hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MOCETINOSTAT DIHYDROBROMIDE 95.00%
5MG
$ 496.12

Total 2 raw suppliers

Chemical Property of Mocetinostat hydrobromide

Chemical Property:

PSA：105.82000
LogP:6.62860

Purity/Quality:

97% ^*data from raw suppliers

MOCETINOSTAT DIHYDROBROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Mocetinostat hydrobromide

There total 4 articles about Mocetinostat hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 726169-73-9
mocetinostat

: 944537-89-7
N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide dihydrobromide

Guidance literature:: With hydrogen bromide; In ethanol; at 0 - 10 ℃; for 3h;

Reference yield:

: 350-03-8
methyl-3-pyridylketone

: 944537-89-7
N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide dihydrobromide

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / 18 h / 110 °C / Reflux

2.1: sodium methylate / methanol / 48 h / Reflux

2.2: 23 h / Reflux

3.1: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dimethyl sulfoxide / 20.6 h / 20 °C

4.1: hydrogen bromide / ethanol / 3 h / 0 - 10 °C

With hydrogen bromide; sodium methylate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In methanol; ethanol; dimethyl sulfoxide;

Reference yield:

: 55314-16-4,75415-01-9,123367-26-0
(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

: 944537-89-7
N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide dihydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium methylate / methanol / 48 h / Reflux

1.2: 23 h / Reflux

2.1: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dimethyl sulfoxide / 20.6 h / 20 °C

3.1: hydrogen bromide / ethanol / 3 h / 0 - 10 °C

With hydrogen bromide; sodium methylate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In methanol; ethanol; dimethyl sulfoxide;