ETHYL 2-ACETAMIDO-2-(DIMETHOXYPHOSPHORYL)ACETATE

Base Information

Chemical Name:ETHYL 2-ACETAMIDO-2-(DIMETHOXYPHOSPHORYL)ACETATE
CAS No.:1227060-32-3
Molecular Formula:C8H16NO6P
Molecular Weight:253.192
Hs Code.:
Mol file:1227060-32-3.mol

Synonyms:ETHYL 2-ACETAMIDO-2-(DIMETHOXYPHOSPHORYL)ACETATE;Ethyl N-acyl-2-(dimethoxyphosphoryl)glycinate

Suppliers and Price of ETHYL 2-ACETAMIDO-2-(DIMETHOXYPHOSPHORYL)ACETATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of ETHYL 2-ACETAMIDO-2-(DIMETHOXYPHOSPHORYL)ACETATE

Chemical Property:

PSA：100.74000
LogP:0.88850

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ETHYL 2-ACETAMIDO-2-(DIMETHOXYPHOSPHORYL)ACETATE

There total 1 articles about ETHYL 2-ACETAMIDO-2-(DIMETHOXYPHOSPHORYL)ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 819877-81-1
C₆H₁₀ClNO₃

: 121-45-9
phosphorous acid trimethyl ester

: 1227060-32-3
ethyl N-acyl-2-(dimethoxyphosphoryl)glycinate

Guidance literature:: In Isopropyl acetate; at 55 ℃;
DOI:10.1021/op1000594

Reference yield: 90.4%

: 67-36-7
4-phenoxy benzaldehyde

: 1227060-32-3
ethyl N-acyl-2-(dimethoxyphosphoryl)glycinate

: C₁₉H₁₉NO₄

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield:

: 1227060-32-3
ethyl N-acyl-2-(dimethoxyphosphoryl)glycinate

: 100-52-7
benzaldehyde

: 2361-96-8
ethyl N-acetyl-(L)-phenylalaninate

Guidance literature:: Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 20 °C

2: bis(norbornadiene)rhodium(l)tetrafluoroborate; (3S,3'S)-3,3'-di-tert-butyl-2,2',3,3'-tetrahydro-4,4'-bibenzo[d][1,3]oxaphosphole; hydrogen / methanol / 24 h / 20 °C / 5171.62 Torr / Autoclave

With bis(norbornadiene)rhodium(l)tetrafluoroborate; (3S,3'S)-3,3'-di-tert-butyl-2,2',3,3'-tetrahydro-4,4'-bibenzo[d][1,3]oxaphosphole; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; dichloromethane;
DOI:10.1021/acs.orglett.8b00139