TOPOTECAN-D6

Base Information

Chemical Name:TOPOTECAN-D6
CAS No.:1044904-10-0
Molecular Formula:C₂₃H₂₃N₃O₅
Molecular Weight:427.405
Hs Code.:
Mol file:1044904-10-0.mol

Synonyms:TOPOTECAN-D6;(4S)-10-[[Di(methyl-d3)amino]methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[346-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;SKF-104864A-d6;(4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’,6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Hycamtin-d6;NSC-609669-d6;(4S)-10-[[Di(methyl-d3)amino]methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Suppliers and Price of TOPOTECAN-D6

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Topotecan-d6
1mg
$ 460.00

TRC
Topotecan-d6
10mg
$ 1455.00

Medical Isotopes, Inc.
Topotecan-d6
1 mg
$ 750.00

Cayman Chemical
Topotecan-d6
1mg
$ 245.00

Cayman Chemical
Topotecan-d6
500μg
$ 129.00

American Custom Chemicals Corporation
TOPOTECAN-D6 95.00%
100MG
$ 1871.10

American Custom Chemicals Corporation
TOPOTECAN-D6 95.00%
10MG
$ 739.20

American Custom Chemicals Corporation
TOPOTECAN-D6 95.00%
1MG
$ 545.00

Total 5 raw suppliers

Chemical Property of TOPOTECAN-D6

Chemical Property:

Melting Point:213-218°C (dec)
PSA：104.89000
LogP:1.84680
Storage Temp.:-20°C Freezer

Purity/Quality:

97% ^*data from raw suppliers

Topotecan-d6 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Topotecan-d6 is intended for use as an internal standard for the quantification of topotecan by GC- or LC-MS. Topotecan is an inhibitor of DNA topoisomerase I and a derivative of the DNA topoisomerase I inhibitor camptothecin . Topotecan inhibits DNA topoisomerase I in human MCF-7 breast and DU145 prostate cancer cells with IC50 values of 13 and 2 nM, respectively, in a cell-based luciferase reporter assay. Topotecan induces cytotoxicity and DNA damage in HT-29 human colon adenocarcinoma cells (IC50s = 33 and 280 nM, respectively). Formulations containing topotecan have been used in the treatment of small-cell lung cancer.
Uses Labelled Topotecan. A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic Labelled Topotecan (T542500). A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic.

Technology Process of TOPOTECAN-D6

There total 1 articles about TOPOTECAN-D6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: