Dyfoxon

Base Information

• Chemical Name: Dyfoxon
• CAS No.: 7526-28-5
• Molecular Formula: C10H15 O3 P
• Molecular Weight: 214.198061
• DSSTox Substance ID: DTXSID40996731
• Mol file: 7526-28-5.mol

Synonyms:dyfonate-oxon;dyfoxon;fonofos oxon

Chemical Property of Dyfoxon

Chemical Property:

• Vapor Pressure: 0.00483mmHg at 25°C
• Boiling Point: 285.4°C at 760 mmHg
• Flash Point: 140.4°C
• PSA: 45.34000
• Density: 1.107g/cm³
• LogP: 3.31490
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 214.07588133
• Heavy Atom Count: 14
• Complexity: 200

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOP(=O)(CC)OC1=CC=CC=C1

Technology Process of Dyfoxon

There total 3 articles about Dyfoxon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethylphosphonic acid diethyl ester (78-38-6) + phenol (108-95-2,27073-41-2) → ethyl phenyl ethylphosphonate (7526-28-5)

Guidance literature:

ethylphosphonic acid diethyl ester; With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 20 ℃; for 0.166667h; Sealed tube;

phenol; In dichloromethane; at 20 ℃; for 0.5h; Sealed tube;

DOI:10.1002/anie.201802082

Reference yield:

paraoxon (546-71-4,8053-54-1) + sodium phenoxide (139-02-6) → ethyl phenyl ethylphosphonate (7526-28-5) + p-nitrophenolate (14609-74-6)

Guidance literature:

In water; at 25 ℃; Further Variations:; Reaction partners; Reagents; Solvents; Temperatures; Kinetics; Activation energy;

DOI:10.1007/BF02498265

Reference yield:

diethyl phenyl phosphite (4894-60-4) + ethyl iodide (75-03-6) → ethyl phenyl ethylphosphonate (7526-28-5)

Guidance literature:

at 110 ℃; Kinetics; Isomerisierung;

upstream raw materials:

diethyl phenyl phosphite

ethyl iodide

paraoxon

sodium phenoxide

Refernces

• 1、 Bel'skii,Valeeva. "Kinetics of reactions of ethyl p-nitrophenyl ethylphosphonate with anionic nucleophiles in a detergentless microemulsion". . p. 2236 - 2239. Retrieved 2007/10/03.