5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-,ethylester(9CI)

Base Information

Chemical Name:5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-,ethylester(9CI)
CAS No.:401648-34-8
Molecular Formula:C16H20N2O3
Molecular Weight:288.346
Hs Code.:
Mol file:401648-34-8.mol

Synonyms:5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-,ethylester(9CI)

Suppliers and Price of 5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-,ethylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-,ethylester(9CI)

Chemical Property:

PSA：70.92000
LogP:2.62660

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-,ethylester(9CI)

There total 3 articles about 5-Pyrimidinecarboxylicacid,1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-,ethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 100-52-7
benzaldehyde

: 3249-68-1
ethyl butyroyl acetate

: 57-13-6
urea

: 401648-34-8
ethyl 1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propylpyrimidine-5-carboxylate

Guidance literature:: With copper(II) bis(trifluoromethanesulfonate); In ethanol; at 100 ℃; for 1h; Microwave irradiation; Inert atmosphere;
DOI:10.1016/j.tetlet.2010.10.150

Reference yield: 74.0%

: 1147294-73-2
2-oxo-4-phenyl-6-propyl-1,2-dihydropyrimidine-5-carboxylic acid ethyl ester

: 401648-34-8
ethyl 1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propylpyrimidine-5-carboxylate

Guidance literature:: With iodine; magnesium; In methanol; at 50 ℃; for 26h; chemoselective reaction;
DOI:10.1016/j.tetlet.2009.02.165

Reference yield: 71.0%

: 74-96-4
ethyl bromide

: 123237-03-6,5395-36-8
ethyl 6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylate

: 401648-34-8
ethyl 1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propylpyrimidine-5-carboxylate

Guidance literature:: ethyl 6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -10 - 20 ℃;

ethyl bromide; In tetrahydrofuran; hexane; at 0 - 20 ℃;
DOI:10.1021/jo050675q