tert-butyl 4-(N-isopropylacetaMido)piperidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(N-isopropylacetaMido)piperidine-1-carboxylate
CAS No.:1246249-81-9
Molecular Formula:C15H28N2O3
Molecular Weight:284.39442
Hs Code.:
Mol file:1246249-81-9.mol

Synonyms:tert-butyl 4-(N-isopropylacetaMido)piperidine-1-carboxylate

Suppliers and Price of tert-butyl 4-(N-isopropylacetaMido)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
tert-Butyl4-(N-isopropylacetamido)piperidine-1-carboxylate 95%
1g
$ 839.00

Alichem
tert-Butyl4-(N-isopropylacetamido)piperidine-1-carboxylate
1g
$ 758.10

Total 5 raw suppliers

Chemical Property of tert-butyl 4-(N-isopropylacetaMido)piperidine-1-carboxylate

Chemical Property:

Boiling Point:389.1±31.0 °C(Predicted)
PKA:-0.62±0.20(Predicted)
PSA：49.85000
Density:1.04±0.1 g/cm3(Predicted)
LogP:2.58070

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl4-(N-isopropylacetamido)piperidine-1-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-(N-isopropylacetaMido)piperidine-1-carboxylate

There total 2 articles about tert-butyl 4-(N-isopropylacetaMido)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 534595-51-2
tert-butyl 4-(isopropylamino)piperidine-1-carboxylate

: 75-36-5
acetyl chloride

: 1246249-81-9
tert-butyl 4-(N-isopropylacetamido)piperidine-1-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 2.5h;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 1246249-81-9
tert-butyl 4-(N-isopropylacetamido)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; sodium cyanoborohydride / methanol / 1 h / 20 °C

2: triethylamine / dichloromethane / 2.5 h / 0 °C

With sodium cyanoborohydride; acetic acid; triethylamine; In methanol; dichloromethane;

Reference yield:

: 1246249-81-9
tert-butyl 4-(N-isopropylacetamido)piperidine-1-carboxylate

: 1246249-83-1
N-(1-(4-formylphenyl)piperidin-4-yl)-N-isopropylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 120 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;