N,N-Diethyl-4-[hydroxy(3-methoxyphenyl)methyl]benzamide

Base Information

Chemical Name:N,N-Diethyl-4-[hydroxy(3-methoxyphenyl)methyl]benzamide
CAS No.:186094-06-4
Molecular Formula:C19H23NO3
Molecular Weight:313.397
Hs Code.:
DSSTox Substance ID:DTXSID30440137
Mol file:186094-06-4.mol

Synonyms:186094-06-4;rac-4-(3'-Methoxy-alpha-hydroxybenzyl)-N,N-diethylbenzamide;N,N-diethyl-4-[hydroxy-(3-methoxyphenyl)methyl]benzamide;N,N-Diethyl-4-[hydroxy(3-methoxyphenyl)methyl]benzamide;SCHEMBL1989199;DTXSID30440137;OLCRRCZCYBBWQA-UHFFFAOYSA-N;FT-0671241;rac-4-(3'-Methoxy-?-hydroxybenzyl)-N,N-diethylbenzamide;rac-4-(3'-Methoxy- alpha -hydroxybenzyl)-N,N-diethylbenzamide

Suppliers and Price of N,N-Diethyl-4-[hydroxy(3-methoxyphenyl)methyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rac-4-(3’-Methoxy-α-hydroxybenzyl)-N,N-diethylbenzamide
100mg
$ 155.00

TRC
rac-4-(3’-Methoxy-α-hydroxybenzyl)-N,N-diethylbenzamide
1g
$ 1230.00

American Custom Chemicals Corporation
N,N-DIETHYL-4-[HYDROXY(3-METHOXYPHENYL)METHYL]BENZAMIDE 95.00%
5MG
$ 501.39

Total 2 raw suppliers

Chemical Property of N,N-Diethyl-4-[hydroxy(3-methoxyphenyl)methyl]benzamide

Chemical Property:

Melting Point:80-82°C
PSA：49.77000
LogP:3.25890
Solubility.:Dichloromethane, Methanol
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:313.16779360
Heavy Atom Count:23
Complexity:362

Purity/Quality:

97% ^*data from raw suppliers

rac-4-(3’-Methoxy-α-hydroxybenzyl)-N,N-diethylbenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1=CC=C(C=C1)C(C2=CC(=CC=C2)OC)O
Uses rac-4-(3’-Methoxy-α-hydroxybenzyl)-N,N-diethylbenzamide (cas# 186094-06-4) is a compound useful in organic synthesis.

Technology Process of N,N-Diethyl-4-[hydroxy(3-methoxyphenyl)methyl]benzamide

There total 13 articles about N,N-Diethyl-4-[hydroxy(3-methoxyphenyl)methyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 156727-77-4
N,N-diethyl-4-(3-methoxybenzoyl)benzamide

: 186094-06-4
(±)-4-[hydroxy-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide

Guidance literature:: N,N-diethyl-4-(3-methoxybenzoyl)benzamide; With sodium tetrahydroborate; In ethanol; water; at 20 ℃; for 2h;

With acetic acid; pH=5;

Reference yield: 91.0%

: 58287-77-7
N,N-diethyl-4-formylbenzamide

: 36282-40-3
(3-methoxyphenyl)magnesium bromide

: 186094-06-4
(±)-4-[hydroxy-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide

Guidance literature:: In tetrahydrofuran; for 1h;
DOI:10.1021/jm9903895

Reference yield: 37.0%

: 2398-37-0
3-methoxyphenyl bromide

: 58287-77-7
N,N-diethyl-4-formylbenzamide

: 186094-06-4
(±)-4-[hydroxy-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide

Guidance literature:: 3-methoxyphenyl bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

N,N-diethyl-4-formylbenzamide; In tetrahydrofuran; hexane; for 1h; Further stages.;
DOI:10.1021/jm000228x