Technology Process of 4-[(4-piperidinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
There total 8 articles about 4-[(4-piperidinyl)-3-methoxybenzyl]-N,N-diethylbenzamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
acetic acid;
for 10h;
under 3102.89 Torr;
DOI:10.1021/jm9903895
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 65 percent / titanium(IV) chloride; zinc powder / 1,2-dimethoxy-ethane / 4 h / Heating
2: 70 percent / H2 / 10 percent Pd/C / acetic acid / 24 h / 3102.89 Torr
3: 82 percent / H2 / 30 percent Pd/C / acetic acid / 10 h / 3102.89 Torr
With
hydrogen; titanium tetrachloride; zinc;
palladium on activated charcoal;
In
1,2-dimethoxyethane; acetic acid;
1: Substitution / 2: Catalytic hydrogenation / 3: Catalytic hydrogenation;
DOI:10.1021/jm9903895
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 91 percent / tetrahydrofuran / 1 h
2: 100 percent / manganese(IV) oxide / CH2Cl2 / 3 h / Heating
3: 65 percent / titanium(IV) chloride; zinc powder / 1,2-dimethoxy-ethane / 4 h / Heating
4: 70 percent / H2 / 10 percent Pd/C / acetic acid / 24 h / 3102.89 Torr
5: 82 percent / H2 / 30 percent Pd/C / acetic acid / 10 h / 3102.89 Torr
With
manganese(IV) oxide; hydrogen; titanium tetrachloride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; acetic acid;
1: Grignard reaction / 2: Oxidation / 3: Substitution / 4: Catalytic hydrogenation / 5: Catalytic hydrogenation;
DOI:10.1021/jm9903895
