2,4,6-Trichlorophenyl forMate

Base Information

• Chemical Name: 2,4,6-Trichlorophenyl forMate
• CAS No.: 4525-65-9
• Molecular Formula: C7H3Cl3O2
• Molecular Weight: 225.459
• Mol file: 4525-65-9.mol

Synonyms:2,4,6-Trichlorophenyl forMate

Chemical Property of 2,4,6-Trichlorophenyl forMate

Chemical Property:

• Melting Point: 81.0 to 85.0 °C
• Boiling Point: 281.2±40.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.537±0.06 g/cm3(Predicted)
• LogP: 3.81790
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: soluble in Toluene

Purity/Quality:

97% ^*data from raw suppliers

2,4,6-Trichlorophenyl Formate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,6-Trichlorophenyl forMate

There total 2 articles about 2,4,6-Trichlorophenyl forMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

formic acid (64-18-6) + 2,4,6-Trichlorophenol (88-06-2,67471-29-8) → (2,4,6-trichlorophenyl) formate (4525-65-9)

Guidance literature:

formic acid; With acetic anhydride; at 20 - 60 ℃; for 1h; Inert atmosphere;

2,4,6-Trichlorophenol; With sodium acetate; Inert atmosphere;

DOI:10.1021/ol302593z

Reference yield: 95.0%

formyl acetic anhydride (2258-42-6) + 2,4,6-Trichlorophenol (88-06-2,67471-29-8) → (2,4,6-trichlorophenyl) formate (4525-65-9)

Guidance literature:

With sodium acetate; In toluene; at 0 - 20 ℃; for 0.666667h; Inert atmosphere;

DOI:10.15227/orgsyn.091.0039

Reference yield: 93.0%

Ethyl 4-bromobenzoate (5798-75-4) + (2,4,6-trichlorophenyl) formate (4525-65-9) → 2,4,6-trichlorophenyl 4-ethoxycarbonylbenzoate (1402012-65-0)

Guidance literature:

With bis(benzonitrile)palladium(II) dichloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1248/cpb.c18-00042

upstream raw materials:

formic acid

2,4,6-Trichlorophenol

formyl acetic anhydride

Downstream raw materials:

For-D-Met-His-Phe-OMe

For-Met-His-Phe-OBzl

2,4,6-trichlorophenyl benzoate

2,4,6-trichlorophenyl 3,4-dihydronaphthalene-2-carboxylate