Tert-butyl 2-(4-hydroxyphenyl)acetate

Base Information

Chemical Name:Tert-butyl 2-(4-hydroxyphenyl)acetate
CAS No.:16010-88-1
Molecular Formula:C₁₂H₁₆O₃
Molecular Weight:208.257
Hs Code.:
European Community (EC) Number:825-769-7
Nikkaji Number:J358.326K
Mol file:16010-88-1.mol

Synonyms:tert-butyl 2-(4-hydroxyphenyl)acetate;16010-88-1;4-Hydroxy phenyl acetic acid-t-butyl ester;t-butyl p-hydroxyphenylacetate;SCHEMBL1283948;t-Butyl 4-hydroxy-phenylacetate;NNGDLOYUAYPSNM-UHFFFAOYSA-N;tert-butyl(4-hydroxyphenyl)acetate;tert-butyl2-(4-hydroxyphenyl)acetate;AKOS018719503;BS-33922;4-Hydroxy phenyl acetic acid tert-butyl ester;EN300-174247;G28349;A1-09042

Suppliers and Price of Tert-butyl 2-(4-hydroxyphenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Tert-butyl 2-(4-hydroxyphenyl)acetate

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:208.109944368
Heavy Atom Count:15
Complexity:209

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CC1=CC=C(C=C1)O

Technology Process of Tert-butyl 2-(4-hydroxyphenyl)acetate

There total 16 articles about Tert-butyl 2-(4-hydroxyphenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 106-41-2
4-bromo-phenol

: 51656-70-3
(2-tert-butoxy-2-oxoethyl)zinc(II) bromide

: 16010-88-1
tert-butyl 2-(4-hydroxyphenyl)acetate

Guidance literature:: 4-bromo-phenol; With potassium hydride; In tetrahydrofuran; at 20 ℃; for 0.166667h;

(2-tert-butoxy-2-oxoethyl)zinc(II) bromide; With {[P(t-Bu)3]PdBr}2; In tetrahydrofuran; at 20 ℃; for 4h;
DOI:10.1021/ja036792p

Reference yield: 91.0%

: 106-41-2
4-bromo-phenol

: tert-butoxycarbonylmethylzinc bromide tetrahydrofuran salt

: 16010-88-1
tert-butyl 2-(4-hydroxyphenyl)acetate

Guidance literature:: 4-bromo-phenol; With potassium hydride; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere; Sealed tube;

tert-butoxycarbonylmethylzinc bromide tetrahydrofuran salt; With di-μ-bromobis(tri-tert-butylphosphino)dipalladium(I); In tetrahydrofuran; at 20 ℃; for 4h; Concentration; Inert atmosphere; Sealed tube;
DOI:10.1021/jo401476f

Reference yield: 88.0%

: tert-butyl 2-(4-(allyloxy)phenyl)acetate

: 16010-88-1
tert-butyl 2-(4-hydroxyphenyl)acetate

Guidance literature:: With vitamin B₁₂; ammonium chloride; zinc; In methanol; at 60 ℃; for 20h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.7b01012