Ethyl 4-(2-chloro-3-pyridyl)-4-oxobutyrate

Base Information

Chemical Name:Ethyl 4-(2-chloro-3-pyridyl)-4-oxobutyrate
CAS No.:852063-32-2
Molecular Formula:C11H12ClNO3
Molecular Weight:241.67
Hs Code.:
DSSTox Substance ID:DTXSID90470278
Wikidata:Q82298321
Mol file:852063-32-2.mol

Synonyms:852063-32-2;ETHYL 4-(2-CHLORO-3-PYRIDYL)-4-OXOBUTYRATE;ethyl 4-(2-chloropyridin-3-yl)-4-oxobutanoate;MFCD02260480;SCHEMBL13116787;DTXSID90470278;CJB06332;AKOS016018759;ETHYL4-(2-CHLORO-3-PYRIDYL)-4-OXOBUTYRATE

Suppliers and Price of Ethyl 4-(2-chloro-3-pyridyl)-4-oxobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
Ethyl4-(2-chloro-3-pyridyl)-4-oxobutyrate 97%
5g
$ 1470.00

Rieke Metals
Ethyl4-(2-chloro-3-pyridyl)-4-oxobutyrate 97%
2g
$ 723.00

Rieke Metals
Ethyl4-(2-chloro-3-pyridyl)-4-oxobutyrate 97%
1g
$ 478.00

Matrix Scientific
Ethyl 4-(2-chloro-3-pyridyl)-4-oxobutyrate
1g
$ 517.00

American Custom Chemicals Corporation
ETHYL 4-(2-CHLORO-3-PYRIDYL)-4-OXOBUTYRATE 95.00%
10G
$ 3638.25

American Custom Chemicals Corporation
ETHYL 4-(2-CHLORO-3-PYRIDYL)-4-OXOBUTYRATE 95.00%
5G
$ 2243.59

American Custom Chemicals Corporation
ETHYL 4-(2-CHLORO-3-PYRIDYL)-4-OXOBUTYRATE 95.00%
1G
$ 617.40

Total 3 raw suppliers

Chemical Property of Ethyl 4-(2-chloro-3-pyridyl)-4-oxobutyrate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:362.418°C at 760 mmHg
Flash Point:172.985°C
Density:1.235g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:241.0505709
Heavy Atom Count:16
Complexity:258

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4-(2-chloro-3-pyridyl)-4-oxobutyrate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CCC(=O)C1=C(N=CC=C1)Cl

Technology Process of Ethyl 4-(2-chloro-3-pyridyl)-4-oxobutyrate

There total 4 articles about Ethyl 4-(2-chloro-3-pyridyl)-4-oxobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 880769-86-8
ethyl 4-(2-chloropyridin-3-yl)-4-hydroxybutyrate

: 852063-32-2
ethyl 4-(2-chloropyridin-3-yl)-4-oxobutyrate

Guidance literature:: With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 6h;
DOI:10.1039/b515385a

Reference yield: 36.0%

: 852063-31-1
ethyl 4-(2-chloropyridin-3-yl)-4-hydroxybut-2-ynoate

: 852063-32-2
ethyl 4-(2-chloropyridin-3-yl)-4-oxobutyrate

Guidance literature:: ethyl 4-(2-chloropyridin-3-yl)-4-hydroxybut-2-ynoate; With hydrogen; palladium on activated charcoal;

With pyridinium chlorochromate;
DOI:10.3390/90600472

Reference yield:

: 36404-88-3
2-chloro-3-carbaldehydepyridine

: 852063-32-2
ethyl 4-(2-chloropyridin-3-yl)-4-oxobutyrate

Guidance literature:: Multi-step reaction with 3 steps

1.1: LiHMDS / tetrahydrofuran / 0.25 h / -78 °C

1.2: 92 percent / tetrahydrofuran / 5 h / -78 °C

2.1: 48 percent / hydrogen / Pd/C / methanol / 5 h / atmospheric pressure

3.1: 67 percent / pyridinium chlorochromate / CH₂Cl₂ / 6 h / 20 °C

With hydrogen; pyridinium chlorochromate; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1039/b515385a