Methyl 2-(4-hydroxyphenyl)benzoate

Base Information

Chemical Name:Methyl 2-(4-hydroxyphenyl)benzoate
CAS No.:170304-68-4
Molecular Formula:C₁₄H₁₂O₃
Molecular Weight:228.247
Hs Code.:2922299090
DSSTox Substance ID:DTXSID40569863
Wikidata:Q82457109
Mol file:170304-68-4.mol

Synonyms:Methyl 2-(4-hydroxyphenyl)benzoate;170304-68-4;Methyl 4'-hydroxy-[1,1'-biphenyl]-2-carboxylate;Methyl4'-hydroxy-[1,1'-biphenyl]-2-carboxylate;p-hydroxyphenyl methyl benzoate;SCHEMBL8923988;DTXSID40569863;VGA30468;MFCD21609727;AKOS016008427;BS-27484;CS-0212033;Methyl 4'-hydroxy[1,1'-biphenyl]-2-carboxylate

Suppliers and Price of Methyl 2-(4-hydroxyphenyl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-(4-Hydroxyphenyl)benzoate
100mg
$ 155.00

Crysdot
Methyl4'-hydroxy-[1,1'-biphenyl]-2-carboxylate 95+%
1g
$ 330.00

American Custom Chemicals Corporation
METHYL-4'-HYDROXY-[1,1'-BIPHENYL]-2-CARBOXYLATE 95.00%
5MG
$ 502.83

Alichem
Methyl4'-hydroxy-[1,1'-biphenyl]-2-carboxylate
1g
$ 400.00

AK Scientific
Methyl4'-hydroxy-[1,1'-biphenyl]-2-carboxylate
1g
$ 517.00

Total 8 raw suppliers

Chemical Property of Methyl 2-(4-hydroxyphenyl)benzoate

Chemical Property:

PSA：46.53000
LogP:2.84580
Storage Temp.:2-8°C
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:228.078644241
Heavy Atom Count:17
Complexity:256

Purity/Quality:

98%min ^*data from raw suppliers

Methyl2-(4-Hydroxyphenyl)benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC=CC=C1C2=CC=C(C=C2)O

Technology Process of Methyl 2-(4-hydroxyphenyl)benzoate

There total 5 articles about Methyl 2-(4-hydroxyphenyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 67-56-1
methanol

: 67526-82-3
4'-hydroxy-1,1'-biphenyl-2-carboxylic acid

: 170304-68-4
methyl 4'-hydroxy-1,1'-biphenyl-2-carboxylate

Guidance literature:: With hydrogenchloride; for 96h; Ambient temperature;

Reference yield:

: 38053-91-7
2-trimethylsilyloxy-1,3-butadiene

: 33577-99-0
2-ethynyl-benzoic acid methyl ester

: 1251836-88-0
methyl 3’-hydroxybiphenyl-2-carboxylate

: 170304-68-4
methyl 4'-hydroxy-1,1'-biphenyl-2-carboxylate

Guidance literature:: 2-trimethylsilyloxy-1,3-butadiene; 2-ethynyl-benzoic acid methyl ester; With cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane]; zinc(II) iodide; zinc; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In toluene; at 20 ℃; for 1.5h; Overall yield = 79 %; Overall yield = 90.7 mg; Inert atmosphere;
DOI:10.1021/ol4023276

Reference yield:

: 610-97-9
o-iodo-methyl-benzoic acid

: 170304-68-4
methyl 4'-hydroxy-1,1'-biphenyl-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / Pd(PPh₃)4, 2M aq. NaHCO₃ / toluene / 18 h / Heating

2: 80 percent / pyridinium chloride / 4 h / 200 °C

3: 90 percent / HCl gas / 96 h / Ambient temperature

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; pyridine hydrochloride; sodium hydrogencarbonate; In toluene;