67526-82-3

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
4'-Hydroxy-biphenyl-2-carboxylic acid is used as a key intermediate for the synthesis of pharmaceutical and agrochemical products. Its unique structure allows it to be a versatile component in the development of new drugs and pesticides.
Used in Liquid Crystal Preparation:
4'-HYDROXY-BIPHENYL-2-CARBOXYLIC ACID is also used in the preparation of liquid crystals, which are essential in the manufacturing of various electronic devices, such as displays and sensors.
Used in Organic Chemistry Research:
4'-Hydroxy-biphenyl-2-carboxylic acid is utilized as a valuable building block in organic chemistry, enabling researchers to explore its potential applications and reactions in the synthesis of new compounds.
Used in Biological Activity Studies:
4'-Hydroxy-biphenyl-2-carboxylic acid has been studied for its potential biological activities, including its anti-inflammatory and antibacterial properties, making it a promising candidate for further research and development in the field of medicine.

Upstream product

• 88-67-5 2-Iodobenzoic acid 
• 108-95-2 phenol 
• 5720-07-0 4-methoxyphenylboronic acid 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 17103-25-2 methyl 4'-methoxybiphenyl-2-carboxylate 
• 18211-41-1 4'-nitro-[1,1'-biphenyl]-2-carboxylic acid 
• 25829-61-2 4'-aminobiphenyl-2-carboxylic acid 

Downstream Products

• 18110-71-9 4'-methoxybiphenyl-2-carboxylic acid 
• 170304-68-4 methyl 4'-hydroxy-1,1'-biphenyl-2-carboxylate 
• 92-69-3 4-Phenylphenol 
• 1143-62-0 3-Methoxy-6H-dibenzopyran-6-one 

Relevant academic research and scientific papers

Palladium-catalyzed para-selective arylation of phenols with aryl iodides in water

Highly para-selective palladium-catalyzed direct arylation of phenols with aryl iodides was demonstrated by taking advantage of the formal inverse direct arylation strategy. A series of 4-aryl phenols were synthesised by employing water as a green solvent under mild reaction conditions. The Royal Society of Chemistry.

Intramolecular Cyclisations of Biphenyl-2-carboxyl Radicals: Evidence for a Π-State Aroyloxyl Radical

Biphenyl-2-carboxyl radicals generated by homolysis of acyl hypoiodites cyclise intramoleculary giving mainly δ-lactones through Ar2-6 cyclisation. 2'-Alkoxybiphenyl-2-carboxyl radicals do not give the expected Ar1-5 cyclisation product but undergo a homolytic ipso-substitution of the 2'-substituent.The phenanthrene-4-carboxyl radical gives 5H-phenanthropyran-5-one.Consideration of the molecular orbitals involved suggests that the biphenyl-2-carboxyl radicals are in the ?-ground state and have a higher energy, and, therefore, a less thermally accessible Σ-state than the corresponding amido-radicals.It is suggested that acyloxyl radicals which readily decarboxylate have either a Σ-ground state or a thermally accessible excited Σ-state.