Dimethyl cyclobutane-1,3-dicarboxylate

Base Information

Chemical Name:Dimethyl cyclobutane-1,3-dicarboxylate
CAS No.:90199-98-7
Molecular Formula:C₈H₁₂O₄
Molecular Weight:172.181
Hs Code.:
DSSTox Substance ID:DTXSID301240165
Nikkaji Number:J2.865.108B
Mol file:90199-98-7.mol

Synonyms:90199-98-7;dimethyl cyclobutane-1,3-dicarboxylate;1,3-dimethyl cyclobutane-1,3-dicarboxylate;1,3-Cyclobutanedicarboxylic acid, dimethyl ester;MFCD00510137;1,3-dimethyl (1s,3s)-cyclobutane-1,3-dicarboxylate;2398-12-1;1,3-Cyclobutanedicarboxylic acid, dimethyl ester, trans;SCHEMBL12265855;DTXSID301240165;dimethylcyclobutane-1,3-dicarboxylate;AKOS027322292;AM85677;AM85959;PB43795;2398-13-2;AS-78758;SY321945;cis-Dimethyl cyclobutane-1,3-dicarboxylate;CS-0184840;Trans-Dimethyl cyclobutane-1,3-dicarboxylate;D79067;F2147-8292

Suppliers and Price of Dimethyl cyclobutane-1,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Dimethylcyclobutane-1,3-dicarboxylate 95+%
1g
$ 520.00

ACHEMBLOCK
1,3-dimethylcyclobutane-1,3-dicarboxylate 97%
5G
$ 1525.00

Aaron Chemicals
1,3-dimethylcyclobutane-1,3-dicarboxylate 98%
5g
$ 1167.00

Aaron Chemicals
1,3-dimethylcyclobutane-1,3-dicarboxylate 98%
1g
$ 393.00

Total 9 raw suppliers

Chemical Property of Dimethyl cyclobutane-1,3-dicarboxylate

Chemical Property:

PSA：52.60000
LogP:0.35860
XLogP3:0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:172.07355886
Heavy Atom Count:12
Complexity:169

Purity/Quality:

99%, ^*data from raw suppliers

Dimethylcyclobutane-1,3-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CC(C1)C(=O)OC

Technology Process of Dimethyl cyclobutane-1,3-dicarboxylate

There total 14 articles about Dimethyl cyclobutane-1,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 62184-63-8
cyclobutane-1,3-dicarboxylic acid

: 90199-98-7
cyclobutane-1,3-dicarboxylic acid dimethyl ester

Guidance literature:: With sulfuric acid; In methanol; at 75 ℃;

Reference yield:

: 15760-35-7
3-methylenecyclobutanecarbonitrile

: 90199-98-7
cyclobutane-1,3-dicarboxylic acid dimethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium hydroxide / ethanol; water / 105 °C

2.1: dmap / tetrahydrofuran / 20 °C

3.1: dimethylsulfide borane complex; dimethylsulfide / tetrahydrofuran / 4 h / -20 - 20 °C / Inert atmosphere

3.2: 0.25 h / -20 - -10 °C

3.3: 2 h / -20 - -10 °C

4.1: nitric acid / water / 3 h / 120 °C

5.1: sulfuric acid / methanol / 75 °C

With dmap; dimethylsulfide; dimethylsulfide borane complex; sulfuric acid; nitric acid; potassium hydroxide; In tetrahydrofuran; methanol; ethanol; water;

Reference yield:

: 15760-36-8
3-methylenecyclobutane-1-carboxylic acid

: 90199-98-7
cyclobutane-1,3-dicarboxylic acid dimethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: dmap / tetrahydrofuran / 20 °C

2.1: dimethylsulfide borane complex; dimethylsulfide / tetrahydrofuran / 4 h / -20 - 20 °C / Inert atmosphere

2.2: 0.25 h / -20 - -10 °C

2.3: 2 h / -20 - -10 °C

3.1: nitric acid / water / 3 h / 120 °C

4.1: sulfuric acid / methanol / 75 °C

With dmap; dimethylsulfide; dimethylsulfide borane complex; sulfuric acid; nitric acid; In tetrahydrofuran; methanol; water;