Methyl 3-forMyl-4-Methoxybenzoate

Base Information

• Chemical Name: Methyl 3-forMyl-4-Methoxybenzoate
• CAS No.: 145742-55-8
• Molecular Formula: C10H10O4
• Molecular Weight: 194.187
• Hs Code.: 2918990090
• Mol file: 145742-55-8.mol

Synonyms:Methyl 3-forMyl-4-Methoxybenzoate;3-ForMyl-4-Methoxy-benzoic acid Methyl ester

Chemical Property of Methyl 3-forMyl-4-Methoxybenzoate

Chemical Property:

• Boiling Point: 332.3±27.0 °C(Predicted)
• PSA: 52.60000
• Density: 1.191±0.06 g/cm3(Predicted)
• LogP: 1.29430

Purity/Quality:

97% ^*data from raw suppliers

Methyl 3-formyl-4-methoxybenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-forMyl-4-Methoxybenzoate

There total 9 articles about Methyl 3-forMyl-4-Methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methyl 3-formyl-4-hydroxybenzoate (24589-99-9) + methyl iodide (74-88-4) → methyl 3-formyl-4-methoxybenzoate (145742-55-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1021/acschemneuro.0c00693

Reference yield: 85.0%

methyl 3-formyl-4-hydroxybenzoate (24589-99-9) + dimethyl sulfate (77-78-1) → methyl 3-formyl-4-methoxybenzoate (145742-55-8)

Guidance literature:

With potassium carbonate; In acetone; for 2h; Reflux;

DOI:10.1021/acs.jmedchem.7b01447

Reference yield: 84.1%

→ methyl 3-formyl-4-methoxybenzoate (145742-55-8)

Guidance literature:

With titanium tetrachloride; In dichloromethane; for 4h; Cooling with ice;

upstream raw materials:

3-formyl-4-hydroxybenzoic acid

potassium carbonate

methyl iodide

methyl 3-formyl-4-hydroxybenzoate

Downstream raw materials:

2-methoxy-5-(methoxycarbonyl)benzoic acid

4-methoxy-3-{[4-(3-phenylureido)phenylamino]methyl}-benzoic acid methyl ester

4-methoxy-3-[(4-methyl-piperazin-1-yl)methyl]-benzaldehyde