epichlorohydrin

Base Information

• Chemical Name: epichlorohydrin
• CAS No.: 13403-37-7
• Molecular Formula: C₃H₅ClO
• Molecular Weight: 92.5251
• Mol file: 13403-37-7.mol

Synonyms:

Chemical Property of epichlorohydrin

Chemical Property:

• Melting Point: -26°C
• Refractive Index: 1.4358 (estimate)
• Boiling Point: 84.72°C (rough estimate)
• PSA: 12.53000
• Density: 1.1812
• LogP: 0.62400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of epichlorohydrin

There total 112 articles about epichlorohydrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(S)-1-Acetoxy-2-bromo-3-chloropropane → (R)-(-)-epichlorohydrin (51594-55-9,24969-06-0,13403-37-7)

Guidance literature:

With dmap; potassium carbonate; In ethylene glycol; at 30 ℃; for 0.333333h;

DOI:10.1055/s-1999-2991

Reference yield: 94.0%

3-chloroprop-1-ene (107-05-1) → 1-chloro-3-methoxypropan-2-ol (4151-97-7) + 3-monochloro-1,2-propanediol (96-24-2) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7)

Guidance literature:

With dihydrogen peroxide; TS-1; In methanol; water; 1,2-dichloro-benzene; at 25 - 40 ℃; for 1h; Product distribution / selectivity;

Reference yield: 82.0%

epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → (R)-(-)-epichlorohydrin (51594-55-9,24969-06-0,13403-37-7)

Guidance literature:

With (S,S)-[N,N-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane-diamino]cobalt(III) acetate; water; at 0 - 20 ℃;

DOI:10.1021/jo9810765

upstream raw materials:

1-bromo-3-chloro-propan-2-ol

2,3-Dichloro-1-propanol

1,3-Dichloro-2-propanol

1,3-dichloro-2-acetoxypropane

Downstream raw materials:

4-(3-chloro-2-hydroxy-propoxy)-benzonitrile

triphenyl isocyanurate

1-chloro-3-(4-chloro-3-methylphenoxy)propan-2-ol

1-[4-(2,3-epoxy-propoxy)-2-hydroxy-phenyl]-ethanone