2,3-Dichloro-1-propanol

Base Information

• Chemical Name: 2,3-Dichloro-1-propanol
• CAS No.: 616-23-9
• Deprecated CAS: 82890-22-0
• Molecular Formula: C3H6 Cl2 O
• Molecular Weight: 128.986
• Hs Code.: 29051990
• European Community (EC) Number: 210-470-0
• UN Number: 2810
• UNII: 88I7UKE7IM
• DSSTox Substance ID: DTXSID2024038
• Nikkaji Number: J3.003A
• Wikidata: Q27269940
• ChEMBL ID: CHEMBL1538584
• Mol file: 616-23-9.mol

Synonyms:1-propanol, 2,3-dichloro-;2,3-dichloro-1-propanol;2,3-dichloropropanol;beta-dichlorohydrin;DC1P

Chemical Property of 2,3-Dichloro-1-propanol

Chemical Property:

• Appearance/Colour: clear, colorless liquid
• Vapor Pressure: 0.214mmHg at 25°C
• Melting Point: -29.15°C
• Refractive Index: 1.4835-1.4855
• Boiling Point: 184 °C at 760 mmHg
• PKA: 13.75±0.10(Predicted)
• Flash Point: 98.5 °C
• Density: 1.360
• Storage Temp.: Store below +30°C.
• Solubility.: 1-10g/l
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 127.9795702
• Heavy Atom Count: 6
• Complexity: 32
• Transport DOT Label: Poison

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dichloro-1-propanol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 20-24/25-41
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Halogenated Alcohols
• Canonical SMILES: C(C(CCl)Cl)O
• Uses: An isomer of dichloropropanol; shows metabolite toxicity. 2,3-Dichloro-1-propanol may be employed as carbon and energy supplement for the growth of Pseudomonas putida strain (MC4).

Technology Process of 2,3-Dichloro-1-propanol

There total 64 articles about 2,3-Dichloro-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.414%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 2,3-Dichloro-1-propanol (616-23-9) + 2-chloro-propane-1,3-diol (497-04-1) + 1,3-Dichloro-2-propanol (96-23-1) + 3-monochloro-1,2-propanediol (96-24-2)

Guidance literature:

With hydrogenchloride; hexahydro-2H-oxepin-2-one; In water; at 110 ℃; for 4h; under 6448.83 Torr; Product distribution / selectivity;

Reference yield: 88.2%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 2,3-Dichloro-1-propanol (616-23-9)

Guidance literature:

With hydrogenchloride; Adipic acid; In water; at 105 ℃; for 10h; Reagent/catalyst; Temperature; Concentration;

Reference yield: 69.0%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 2,3-Dichloro-1-propanol (616-23-9) + 1,3-Dichloro-2-propanol (96-23-1) + 3-monochloro-1,2-propanediol (96-24-2)

Guidance literature:

With L-Lactic acid; chlorine; at 110 ℃; for 10h; Reagent/catalyst; Temperature; Time;

upstream raw materials:

diethyl ether

2,3-dichloropropanal

n-hexylmagnesium bromide

chloromethanol

Downstream raw materials:

2,3-dichloropropanoic acid

2,3-dimercaptopropanol

epichlorohydrin

1-phenylpyrazole

Refernces

• 1、 Blake,Moran. "An improved colorimetric procedure for the analysis of vitamin A". . p. 1757 - 1764. Retrieved 1976.
• 2、 -. "Preparation method for 1,3-propylene glycol from glycerol". Paragraph 0066-0076. . Retrieved 2021/04/10.
• 3、 Peng, Xinxin,Xia, Changjiu,Lin, Min,Shu, Xingtian,Zhu, Bin,Wang, Baorong,Zhang, Yao,Luo, Yibin,Mu, Xuhong. "A safer and greener chlorohydrination of allyl chloride with H2O2 and HCl over hollow titanium silicate zeolite". . p. 17 - 25. Retrieved 2017/06/23.