2-(4-Acetamidophenoxy)-N,N,N-trimethylethanaminium bromide

Base Information

• Chemical Name: 2-(4-Acetamidophenoxy)-N,N,N-trimethylethanaminium bromide
• CAS No.: 855945-03-8
• Molecular Formula: C13H21BrN2O2
• Molecular Weight: 317.226
• Mol file: 855945-03-8.mol

Synonyms:2-(4-Acetamidophenoxy)-N,N,N-trimethylethanaminium bromide

Chemical Property of 2-(4-Acetamidophenoxy)-N,N,N-trimethylethanaminium bromide

Chemical Property:

• PSA: 38.33000
• LogP: -1.19300
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Acetamidophenoxy)-N,N,N-trimethylethanaminiumbromide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Acetamidophenoxy)-N,N,N-trimethylethanaminium bromide

There total 2 articles about 2-(4-Acetamidophenoxy)-N,N,N-trimethylethanaminium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

1-bromo-2-(4-acetamidophenoxy)ethane (57011-90-2) + trimethylamine (75-50-3) → (2-(4-acetamidophenoxy)ethyl)trimethylammonium bromide (855945-03-8)

Guidance literature:

In ethanol; butanone; at 20 ℃; for 96h;

DOI:10.1021/ac801429w

Reference yield:

4-acetaminophenol (103-90-2,8055-08-1) → (2-(4-acetamidophenoxy)ethyl)trimethylammonium bromide (855945-03-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / Reflux

2: ethanol; butanone / 96 h / 20 °C

With potassium carbonate; In ethanol; acetonitrile; butanone;

DOI:10.3390/molecules23112994

Reference yield: 45.0%

(2-(4-acetamidophenoxy)ethyl)trimethylammonium bromide (855945-03-8) → 4-(2-(trimethylammonio)ethoxy)benzenaminium bromide chloride

Guidance literature:

With hydrogenchloride; water; for 0.5h; Reflux;

DOI:10.1021/ac801429w

upstream raw materials:

1-bromo-2-(4-acetamidophenoxy)ethane

trimethylamine

4-acetaminophenol

Downstream raw materials:

4-(2-(trimethylammonio)ethoxy)benzenaminium dibromide

Refernces

• 1、 Eggink, Mark,Wijtmans, Maikel,Ekkebus, Reggy,Lingeman, Henk,De Esch, Iwan J. P.,Kool, Jeroen,Niessen, Wilfried M. A.,Irth, Hubertus. "Development of a selective ESI-MS derivatization reagent: Synthesis and optimization for the analysis of aldehydes in biological mixtures". experimental part. p. 9042 - 9051. Retrieved 2009/06/06.