Chloromethyl 4-pentenyl ether

Base Information

• Chemical Name: Chloromethyl 4-pentenyl ether
• CAS No.: 98486-13-6
• Molecular Formula: C6H11ClO
• Molecular Weight: 134.6
• DSSTox Substance ID: DTXSID20405270
• Wikidata: Q82209740
• Mol file: 98486-13-6.mol

Synonyms:Chloromethyl 4-pentenyl ether;5-(chloromethoxy)pent-1-ene;98486-13-6;SCHEMBL5807742;DTXSID20405270;AKOS006378957

Chemical Property of Chloromethyl 4-pentenyl ether

Chemical Property:

• Vapor Pressure: 4.28mmHg at 25°C
• Boiling Point: 153.4°C at 760 mmHg
• Flash Point: 55.5°C
• PSA: 9.23000
• Density: 0.958g/cm³
• LogP: 2.16550
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 134.0498427
• Heavy Atom Count: 8
• Complexity: 54.5

Purity/Quality:

99% ^*data from raw suppliers

CHLOROMETHYL 4-PENTENYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCCCOCCl

Technology Process of Chloromethyl 4-pentenyl ether

There total 1 articles about Chloromethyl 4-pentenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + n-Pent-4-enyl alcohol (821-09-0) → 4-pentenyloxymethylchloride (98486-13-6)

Guidance literature:

With hydrogenchloride;

Reference yield: 80.0%

4-pentenyloxymethylchloride (98486-13-6) + 5'-O-(4-4'-dimethoxytrityl)-N3-benzoyl thymidine (102573-69-3) → 5'-O-dimethoxytrityl-3'-O-(4-pentenyloxymethyl)-N3-benzoyl-thymidine (130867-60-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine;

Reference yield: 65.0%

4-pentenyloxymethylchloride (98486-13-6) + 5'-O-(4-4'-dimethoxytrityl)thymidine (40615-39-2) → 5'-O-dimethoxytrityl-3'-O-(4-pentenyloxymethyl)-thymidine (133510-50-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; at 50 ℃; for 4h;

DOI:10.1016/S0040-4020(01)86429-2

upstream raw materials:

formaldehyd

n-Pent-4-enyl alcohol

Downstream raw materials:

(2S,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-2-methoxy-6-pent-4-enyloxymethoxymethyl-tetrahydro-pyran

5'-O-dimethoxytrityl-3'-O-(4-pentenyloxymethyl)-N³-benzoyl-thymidine

5'-O-dimethoxytrityl-3'-O-(4-pentenyloxymethyl)-thymidine

C₃₈H₄₀N₄O₁₄