Propanoic acid, 2,2-dimethyl-, octahydro-7,8-dihydroxy-1,6-indolizinediyl ester, 1S-(1.alpha.,6.beta.,7.alpha.,8.beta.,8a.beta.)-

Base Information

Chemical Name:Propanoic acid, 2,2-dimethyl-, octahydro-7,8-dihydroxy-1,6-indolizinediyl ester, 1S-(1.alpha.,6.beta.,7.alpha.,8.beta.,8a.beta.)-
CAS No.:156150-85-5
Molecular Formula:C₁₈H₃₁NO₆
Molecular Weight:357.447
Hs Code.:
Mol file:156150-85-5.mol

Synonyms:Propanoic acid, 2,2-dimethyl-, octahydro-7,8-dihydroxy-1,6-indolizinediyl ester, 1S-(1.alpha.,6.beta.,7.alpha.,8.beta.,8a.beta.)-

Suppliers and Price of Propanoic acid, 2,2-dimethyl-, octahydro-7,8-dihydroxy-1,6-indolizinediyl ester, 1S-(1.alpha.,6.beta.,7.alpha.,8.beta.,8a.beta.)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanoic acid, 2,2-dimethyl-, octahydro-7,8-dihydroxy-1,6-indolizinediyl ester, 1S-(1.alpha.,6.beta.,7.alpha.,8.beta.,8a.beta.)-

Chemical Property:

PSA：96.30000
LogP:0.64980

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Propanoic acid, 2,2-dimethyl-, octahydro-7,8-dihydroxy-1,6-indolizinediyl ester, 1S-(1.alpha.,6.beta.,7.alpha.,8.beta.,8a.beta.)-

There total 2 articles about Propanoic acid, 2,2-dimethyl-, octahydro-7,8-dihydroxy-1,6-indolizinediyl ester, 1S-(1.alpha.,6.beta.,7.alpha.,8.beta.,8a.beta.)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 156150-87-7
2,2-Dimethyl-propionic acid (1S,6S,7R,8R,8aR)-6,7,8-tris-methoxymethoxy-octahydro-indolizin-1-yl ester

: 156150-85-5
2,2-Dimethyl-propionic acid (1S,6S,7S,8R,8aS)-6-(2,2-dimethyl-propionyloxy)-7,8-dihydroxy-octahydro-indolizin-1-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄

2: 1.) dibutyltin oxide / 1.) ref., toluene; 2.) -10 deg C

With lithium aluminium tetrahydride; di(n-butyl)tin oxide;
DOI:10.1016/S0040-4039(00)76852-3

Reference yield:

: 3282-30-2
pivaloyl chloride

: 156198-82-2
(1S,6S,7R,8R,8aR)-6,7,8-Tris-methoxymethoxy-octahydro-indolizin-1-ol

: 156150-85-5
2,2-Dimethyl-propionic acid (1S,6S,7S,8R,8aS)-6-(2,2-dimethyl-propionyloxy)-7,8-dihydroxy-octahydro-indolizin-1-yl ester

Guidance literature:: With di(n-butyl)tin oxide; Yield given. Multistep reaction; 1.) ref., toluene; 2.) -10 deg C;
DOI:10.1016/S0040-4039(00)76852-3