N-(3-Fluorophenyl)pivalamide

Base Information

Chemical Name:N-(3-Fluorophenyl)pivalamide
CAS No.:81740-17-2
Molecular Formula:C11H14FNO
Molecular Weight:195.237
Hs Code.:2924299090
DSSTox Substance ID:DTXSID00378973
Wikidata:Q82168595
Mol file:81740-17-2.mol

Synonyms:N-(3-Fluorophenyl)pivalamide;81740-17-2;N-(3-fluorophenyl)-2,2-dimethylpropanamide;N-(3-Fluoro-phenyl)-2,2-dimethyl-propionamide;N-(2,2-Dimethylpropanoyl)-3-fluoroaniline;SCHEMBL3880470;DTXSID00378973;MUTPRGMDSOTCJF-UHFFFAOYSA-N;MFCD00464524;STL260367;AKOS000276981;CS-0190971;N-(3-Fluorophenyl)-2,2-dimethylpropionamide;E89467

Suppliers and Price of N-(3-Fluorophenyl)pivalamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(3-Fluoro-phenyl)-2,2-dimethyl-propionamide
50mg
$ 45.00

Crysdot
N-(3-Fluorophenyl)pivalamide 95+%
10g
$ 417.00

Chemcia Scientific
N-(3-Fluoro-phenyl)-2,2-dimethyl-propionamide ＞95%
5 G
$ 185.00

Aronis compounds
N-(3-fluorophenyl)-2,2-dimethylpropanamide
100mg
$ 80.00

Aronis compounds
N-(3-fluorophenyl)-2,2-dimethylpropanamide
50mg
$ 50.00

Aronis compounds
N-(3-fluorophenyl)-2,2-dimethylpropanamide
10mg
$ 20.00

Alichem
N-(3-Fluorophenyl)pivalamide
5g
$ 216.24

Total 10 raw suppliers

Chemical Property of N-(3-Fluorophenyl)pivalamide

Chemical Property:

PSA：32.59000
LogP:3.45980
Storage Temp.:2-8°C
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:195.105942232
Heavy Atom Count:14
Complexity:210

Purity/Quality:

98%min ^*data from raw suppliers

N-(3-Fluoro-phenyl)-2,2-dimethyl-propionamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)NC1=CC(=CC=C1)F

Technology Process of N-(3-Fluorophenyl)pivalamide

There total 3 articles about N-(3-Fluorophenyl)pivalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 372-19-0
meta-fluoroaniline

: 3282-30-2
pivaloyl chloride

: 81740-17-2
2,2-dimethyl-N-(3-fluorophenyl)propanamide

Guidance literature:: With triethylamine; In diethyl ether; Ambient temperature;
DOI:10.1021/jo960203z

Reference yield: 64.0%

: 1416775-71-7
2,2-dimethyl-N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide

: 81740-17-2
2,2-dimethyl-N-(3-fluorophenyl)propanamide

Guidance literature:: With 1-fluoro-2,4,6-trimethylpyridinium hexafluorophosphate; [Cu(^tBuCN)₂OTf]; silver fluoride; In tetrahydrofuran; at 50 ℃; for 18h; Inert atmosphere;
DOI:10.1021/ja310909q

Reference yield:

: 182344-19-0
3-pivaloylaminophenylboronic acid

: 81740-17-2
2,2-dimethyl-N-(3-fluorophenyl)propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 20 °C / Inert atmosphere; Molecular sieve

2: silver fluoride; (tBuCN)2Cu*OTf; 1-fluoro-2,4,6-trimethylpyridinium hexafluorophosphate / tetrahydrofuran / 18 h / 50 °C / Inert atmosphere

With 1-fluoro-2,4,6-trimethylpyridinium hexafluorophosphate; (tBuCN)2Cu*OTf; silver fluoride; In tetrahydrofuran; diethyl ether;
DOI:10.1021/ja310909q