2-aMino-4-broMo-6-fluorobenzonitrile

Base Information

• Chemical Name: 2-aMino-4-broMo-6-fluorobenzonitrile
• CAS No.: 1279865-14-3
• Molecular Formula: C7H4BrFN2
• Molecular Weight: 215.025
• Hs Code.: 2926907090
• Mol file: 1279865-14-3.mol

Synonyms:2-aMino-4-broMo-6-fluorobenzonitrile

Chemical Property of 2-aMino-4-broMo-6-fluorobenzonitrile

Chemical Property:

• Boiling Point: 314.3±42.0 °C(Predicted)
• PKA: -0.27±0.10(Predicted)
• PSA: 49.81000
• Density: 1.77±0.1 g/cm3(Predicted)
• LogP: 2.62328
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-4-bromo-6-fluorobenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-aMino-4-broMo-6-fluorobenzonitrile

There total 1 articles about 2-aMino-4-broMo-6-fluorobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-bromo-2,6-difluorobenzonitrile (123843-67-4) → 2-amino-4-bromo-6-fluoro-benzonitrile (1279865-14-3)

Guidance literature:

With ammonium hydroxide; In water; isopropyl alcohol; at 80 ℃; for 4h; Microwave irradiation;

Reference yield: 96.0%

2-amino-4-bromo-6-fluoro-benzonitrile (1279865-14-3) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → N'-(5-bromo-2-cyano-3-fluoro-phenyl)-N,N-dimethyl-formamidine (1609962-87-9)

Guidance literature:

at 120 ℃; for 2h;

Reference yield: 96.0%

2-amino-4-bromo-6-fluoro-benzonitrile (1279865-14-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → N'-(5-bromo-2-cyano-3-fluoro-phenyl)-N,N-dimethyl-formamidine (1609962-87-9)

Guidance literature:

With 1,1-dimethoxyethane; at 120 ℃; for 2h;

upstream raw materials:

4-bromo-2,6-difluorobenzonitrile

Downstream raw materials:

N′-[2-cyano-5-[[dimethyl(oxo)-λ⁶-sulfanylidene]amino]-3-hydroxyphenyl]-N,N-dimethylformamidine

N'-(5-bromo-2-cyano-3-fluorophenyl)-N,N-dimethylformamidine

N'-(5-bromo-2-cyano-3-fluorophenyl)-N,N-dimethylformamidine

C₂₀H₂₁FN₄O₄S