5-(2-Chlorophenyl)-2,4-dihydro-2-phenyl-3H-pyrazol-3-one

Base Information

Chemical Name:5-(2-Chlorophenyl)-2,4-dihydro-2-phenyl-3H-pyrazol-3-one
CAS No.:118049-75-5
Molecular Formula:C15H11ClN2O
Molecular Weight:270.71
Hs Code.:
DSSTox Substance ID:DTXSID80701609
Mol file:118049-75-5.mol

Synonyms:118049-75-5;5-(2-CHLOROPHENYL)-2,4-DIHYDRO-2-PHENYL-3H-PYRAZOL-3-ONE;5-(2-chlorophenyl)-2-cyclohex-2-en-1-ylpyrazol-2-ium-3-one;DTXSID80701609;JLCBGBYHCGMXCD-UHFFFAOYSA-N;5-(2-Chlorophenyl)-2-(cyclohex-2-en-1-yl)-3-oxo-3H-pyrazol-2-ium

Suppliers and Price of 5-(2-Chlorophenyl)-2,4-dihydro-2-phenyl-3H-pyrazol-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-(2-CHLOROPHENYL)-2,4-DIHYDRO-2-PHENYL-3H-PYRAZOL-3-ONE 95.00%
5MG
$ 497.08

Total 1 raw suppliers

Chemical Property of 5-(2-Chlorophenyl)-2,4-dihydro-2-phenyl-3H-pyrazol-3-one

Chemical Property:

Boiling Point:400.0±44.0 °C(Predicted)
PKA:1.53±0.50(Predicted)
PSA：32.44000
Density:1.28±0.1 g/cm3(Predicted)
LogP:3.18890
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:273.0794658
Heavy Atom Count:19
Complexity:467

Purity/Quality:: 5-(2-CHLOROPHENYL)-2,4-DIHYDRO-2-PHENYL-3H-PYRAZOL-3-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC=CC(C1)[N+]2=NC(=CC2=O)C3=CC=CC=C3Cl

Technology Process of 5-(2-Chlorophenyl)-2,4-dihydro-2-phenyl-3H-pyrazol-3-one

There total 1 articles about 5-(2-Chlorophenyl)-2,4-dihydro-2-phenyl-3H-pyrazol-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 100-63-0
phenylhydrazine

: 19112-35-7
ethyl (2-chlorobenzoyl)acetate

: 118049-75-5
3-(2-chlorophenyl)-1-phenyl-1H-pyrazol-5(4H)-one

Guidance literature:: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; In ethyl acetate; at 100 ℃; for 0.0833333h; Microwave irradiation; Sealed tube;
DOI:10.1002/ejoc.201300380

Reference yield: 57.0%

: 118049-75-5
3-(2-chlorophenyl)-1-phenyl-1H-pyrazol-5(4H)-one

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 312311-47-0
5-chloro-3-(2-chlorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde

Guidance literature:: With bis(trichloromethyl) carbonate; In chlorobenzene; at 130 ℃; for 4h;
DOI:10.3184/030823410X12766918476516

Reference yield: 41.0%

: 118049-75-5
3-(2-chlorophenyl)-1-phenyl-1H-pyrazol-5(4H)-one

: 3-ethynyl-1-methyl-2-oxoindolin-3-yl acetate

: (S)-3'-(2-chlorophenyl)-1-methyl-1'-phenyl-1'H-spiro[indoline-3,4'-pyrano[2,3-c]pyrazol]-2-one

Guidance literature:: With C₃₂H₂₇N₂P; copper(II) bis(trifluoromethanesulfonate); N-ethyl-N,N-diisopropylamine; In methanol; at -20 ℃; for 24h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/acs.orglett.0c03587