19112-35-7

Basic information

• Product Name: 3-(2-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
• Synonyms: ETHYL (2-CHLOROBENZOYL)ACETATE;ETHYL 3-(2-CHLORO-PHENYL)-3-OXOPROPANOATE;3-(2-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER;Ethyl (o-chlorobenzoyl)acetate;NSC 158136;Ethyl (2-chlorobenzoyl)acetate >=95%
• CAS NO: 19112-35-7
• Molecular Formula: C₁₁H₁₁ClO₃
• Molecular Weight: 226.66
• Product Categories: C10 to C11;Carbonyl Compounds;Esters
• Mol File: 19112-35-7.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 221-222 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.206 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00387mmHg at 25°C
• Refractive Index: n20/D 1.540(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.85±0.46(Predicted)
• CAS DataBase Reference: 3-(2-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER(19112-35-7)
• EPA Substance Registry System: 3-(2-CHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER(19112-35-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 19112-35-7(Hazardous Substances Data)

Usage

Uses

Reactant for:Cerium ammonium nitrate-mediated oxidative couplingHydrosilylation reactionsPreparation of diaryl-substituted pyrazoles as potent CCR2 receptor antagonistsPreparation of potential herbicidal agentsRuthenium-catalyzed asymmetric hydrogenation

InChI:InChI=1/C11H11ClO3/c1-2-15-11(14)7-10(13)8-5-3-4-6-9(8)12/h3-6H,2,7H2,1H3

Upstream product

• 1071-46-1 hydrogen ethyl malonate 
• 609-65-4 o-chlorobenzoyl chloride 
• 3516-73-2 2-Chlor-benzoyl-malonsaeure-diethylester 
• 74476-71-4 ethyl 2-(2-chlorobenzoyl)-3-oxobutanoate 
• 141-97-9 ethyl acetoacetate 
• 37517-78-5 magnesium bis(3-ethoxy-3-oxopropanoate) 
• 118-91-2 ortho-chlorobenzoic acid 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 105-58-8 Diethyl carbonate 
• 1336-21-6 ammonium hydroxide 
• 89-98-5 2-chloro-benzaldehyde 
• 6148-64-7 ethyl potassium malonate 
• 141-78-6 ethyl acetate 
• 67333-74-8 1-(2-chloro-benzoyl)-1H-imidazole 

Downstream Products

• 107327-81-1 3-(2-chloro-benzoyl)-8-methoxy-coumarin 
• 101422-34-8 6-chloro-3-(2-chloro-benzoyl)-coumarin 
• 50671-21-1 α-(2-Chlorbenzoyl)-2-methyl-5-lauroylacetanilid 
• 50671-10-8 2-Cetoxy-α-(2-chlorbenzoyl)-acetanilid 
• 50671-17-5 α-(2-Chlorbenzoyl)-5--2-methoxyacetanilid 
• 50671-01-7 α-(2-Chlorbenzoyl)-5-<α-(2,4-di-t-amylphenoxy)-acetylamino>-2-chloracetanilid 
• 50671-14-2 α-(2-Chlorbenzoyl)-2-(N-methyl-N-octadecylamino)-5-(N-phenylsulfamoyl)-acetanilid 
• 27025-73-6 3-(2-chloro-phenyl)-2H-isoxazol-5-one 
• 60868-43-1 2-(2-chlorobenzoyl)-3-ethoxyacrylic acid ethyl ester 
• 98305-11-4 2-Amino-5-chloro-6-(2-chloro-phenyl)-3H-pyrimidin-4-one 
• 76519-29-4 2-Amino-5-bromo-6-(2-chloro-phenyl)-3H-pyrimidin-4-one 
• 76519-30-7 2-Amino-6-(2-chloro-phenyl)-5-iodo-3H-pyrimidin-4-one 
• 1174527-50-4 ethyl (2-chlorobenzoyl)(4-cyanobutyl)acetate 

Relevant articles and documents

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Double Enzyme-Catalyzed One-Pot Synthesis of Enantiocomplementary Vicinal Fluoro Alcohols

A double-enzyme-catalyzed strategy for the synthesis of enantiocomplementary vicinal fluoro alcohols through a one-pot, three-step process including lipase-catalyzed hydrolysis, spontaneous decarboxylative fluorination, and subsequent ketoreductase-catalyzed reduction was developed. With this approach, β-ketonic esters were converted to the corresponding vicinal fluoro alcohols with high isolated yields (up to 92percent) and stereoselectivities (up to 99percent). This new cascade process addresses some issues in comparison with traditional methods such as environmentally hazardous reaction conditions and low stereoselectivity outcome.

Tetrazolinone compound and application for same

Provided is a tetrazolinone compound given by formula (1) (wherein E represents a 5-membered aromatic hetero group, such as the pyrazolyl group, the thiazolyl group, or the imidazolyl group; R4 and R5 represent hydrogen atoms or the like; R6 represents a C1-12 alkyl group; R7, R8, and R9 represent hydrogen atoms or the like; R10 represents a C1-3 alkyl group, or a C1-3 haloalkyl group; Y represents an oxygen atom or the like; and Q represents an oxygen atom or the like), and having exceptional efficacy in controlling harmful organisms.