3-(3-(Piperidin-1-yl)propyl)-1H-indole

Base Information

Chemical Name:3-(3-(Piperidin-1-yl)propyl)-1H-indole
CAS No.:98132-63-9
Molecular Formula:C₁₆H₂₂N₂
Molecular Weight:242.364
Hs Code.:
DSSTox Substance ID:DTXSID60463056
Wikidata:Q82287787
Mol file:98132-63-9.mol

Synonyms:3-(3-(Piperidin-1-yl)propyl)-1H-indole;98132-63-9;3-(3-piperidin-1-ylpropyl)-1H-indole;3-(3-Piperidin-1-yl-propyl)-1H-indole;3-[3-(piperidin-1-yl)propyl]-1H-indole;3-[3-(PIPERIDIN-1-YL)PROPYL]INDOLE;SCHEMBL2420293;DTXSID60463056;AKOS015967427

Suppliers and Price of 3-(3-(Piperidin-1-yl)propyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(3-PIPERIDIN-1-YL-PROPYL)-1H-INDOLE 95.00%
5MG
$ 505.19

Total 7 raw suppliers

Chemical Property of 3-(3-(Piperidin-1-yl)propyl)-1H-indole

Chemical Property:

PSA：19.03000
LogP:3.52430
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:242.178298710
Heavy Atom Count:18
Complexity:248

Purity/Quality:

98% ^*data from raw suppliers

3-(3-PIPERIDIN-1-YL-PROPYL)-1H-INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CCCC2=CNC3=CC=CC=C32

Technology Process of 3-(3-(Piperidin-1-yl)propyl)-1H-indole

There total 2 articles about 3-(3-(Piperidin-1-yl)propyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 4088-34-0
1-(but-3-en-1-yl)piperidine

: 201230-82-2
carbon monoxide

: 100-63-0
phenylhydrazine

: 98132-63-9
3-(3-(piperidin-1-yl)propyl)-1H-indole

Guidance literature:: 1-(but-3-en-1-yl)piperidine; carbon monoxide; phenylhydrazine; With hydrogen; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; Rh(acac)2(CO)2; In tetrahydrofuran; at 70 ℃; for 72h; under 15001.2 Torr;

With sulfuric acid; for 2h; Heating;
DOI:10.1021/jo050464l

Reference yield:

: 110-89-4
piperidine

: 98132-63-9
3-(3-(piperidin-1-yl)propyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: 76 percent / K₂CO₃; 18-crown-6 / acetonitrile / 12 h / Heating

2.1: XANTHPHOS; H₂ / Rh(acac)2(CO)2 / tetrahydrofuran / 72 h / 70 °C / 15001.2 Torr

2.2: 91 percent / aq. H₂SO₄ / 2 h / Heating

With 18-crown-6 ether; hydrogen; potassium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; Rh(acac)2(CO)2; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jo050464l