Imidazo(2,1-b)thiazol-5(6H)-one, 2,3-dihydro-6-(phenylmethylene)-

Base Information

Chemical Name:Imidazo(2,1-b)thiazol-5(6H)-one, 2,3-dihydro-6-(phenylmethylene)-
CAS No.:129228-59-7
Molecular Formula:C₁₂H₁₀N₂OS
Molecular Weight:230.29
Hs Code.:
DSSTox Substance ID:DTXSID60156118
Wikidata:Q76389620

Synonyms:BRN 4188255;Imidazo(2,1-b)thiazol-5(6H)-one, 2,3-dihydro-6-(phenylmethylene)-;2,3-Dihydro-6-benzylidene-imidazo(2,1-b)thiazol-5(6H)-one;129228-59-7;DTXSID60156118;LS-80689

Suppliers and Price of Imidazo(2,1-b)thiazol-5(6H)-one, 2,3-dihydro-6-(phenylmethylene)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Imidazo(2,1-b)thiazol-5(6H)-one, 2,3-dihydro-6-(phenylmethylene)-

Chemical Property:

Vapor Pressure:4.91E-06mmHg at 25°C
Boiling Point:381.9°Cat760mmHg
Flash Point:184.8°C
Density:1.37g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:230.05138412
Heavy Atom Count:16
Complexity:369

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CSC2=NC(=CC3=CC=CC=C3)C(=O)N21
Isomeric SMILES:C1CSC2=N/C(=C/C3=CC=CC=C3)/C(=O)N21

Technology Process of Imidazo(2,1-b)thiazol-5(6H)-one, 2,3-dihydro-6-(phenylmethylene)-

There total 3 articles about Imidazo(2,1-b)thiazol-5(6H)-one, 2,3-dihydro-6-(phenylmethylene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 911371-94-3
2-(2-Bromo-ethylsulfanyl)-5-[1-phenyl-meth-(Z)-ylidene]-3,5-dihydro-imidazol-4-one

: 129228-59-7
6-[1-Phenyl-meth-(Z)-ylidene]-2,3-dihydro-6H-imidazo[2,1-b]thiazol-5-one

Guidance literature:: With PPA; at 100 - 130 ℃; for 1.5h;
DOI:10.1080/104265090968677

Reference yield:

: 583-46-0
5-benzylidene-2-thiohydantoin

: 129228-59-7
6-[1-Phenyl-meth-(Z)-ylidene]-2,3-dihydro-6H-imidazo[2,1-b]thiazol-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / sodium ethoxide / ethanol / 5 h

2: 60 percent / polyphosphoric acid / 1.5 h / 100 - 130 °C

With PPA; sodium ethanolate; In ethanol;
DOI:10.1080/104265090968677