583-46-0

Basic information

• Product Name: (5E)-5-benzylidene-2-sulfanylidene-imidazolidin-4-one
• Synonyms: (5E)-5-benzylidene-2-sulfanylidene-imidazolidin-4-one;2-Thioxo-4-benzylideneimidazolidine-5-one;5-Benzal-2-thlohydantoin;5-Benzylidene-2-thioxo-4-imidazolidinone;5-Benzylidene-2-thioxoimidazolidin-4-one
• CAS NO: 583-46-0
• Molecular Formula: C₁₀H₈N₂OS
• Molecular Weight: 204.25
• Mol File: 583-46-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.37g/cm³
• Refractive Index: 1.702
• CAS DataBase Reference: (5E)-5-benzylidene-2-sulfanylidene-imidazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5E)-5-benzylidene-2-sulfanylidene-imidazolidin-4-one(583-46-0)
• EPA Substance Registry System: (5E)-5-benzylidene-2-sulfanylidene-imidazolidin-4-one(583-46-0)

Safety Data

• Hazardous Substances Data: 583-46-0(Hazardous Substances Data)

Usage

General Description

(5E)-5-benzylidene-2-sulfanylidene-imidazolidin-4-one is a chemical compound with a molecular formula C11H11NOS. It is a heterocyclic organic compound with a five-membered ring containing both sulfur and nitrogen atoms. This chemical may have potential applications in the pharmaceutical and agrochemical industries due to its unique structure and potential biological activities. Additionally, it is important to handle this compound with care, as it may have specific safety and handling guidelines due to its potential reactivity and toxicity.

InChI:InChI=1/C10H8N2OS/c13-9-8(11-10(14)12-9)6-7-4-2-1-3-5-7/h1-6H,(H2,11,12,13,14)/b8-6+

Upstream product

• 110-86-1 pyridine 
• 584-26-9 1-acetyl-2-thiohydantoin 
• 100-52-7 benzaldehyde 
• 503-87-7 2-thiohydantoin 
• 581-55-5 benzylidene 1,1-diacetate 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 
• 588-64-7 benzaldehyde phenylhydrazone 
• 872827-71-9 4-benzylidene-2-ethylsulfanyl-4H-thiazol-5-one 
• 577-47-9 1-benzoyl-2-thioxo-imidazolidin-4-one 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 1147550-11-5 ammonium thiocyanate 
• 56-40-6 glycine 
• 17356-08-0 thiourea 

Downstream Products

• 17886-50-9 (5Z)-5-benzylidene-2-ethylsulfanyl-3,5-dihydro-4H-imidazol-4-one 
• 111064-20-1 3-ethyl-2-ethylmercapto-5-benzylidene-3,5-dihydro-imidazol-4-one 
• 108798-13-6 5-benzylidene-2-propylmercapto-3,5-dihydro-imidazol-4-one 
• 145693-93-2 5-benzylidene-2-methylsulfanyl-3,5-dihydro-imidazol-4-one 
• 82319-33-3 5-benzylidene-3-methyl-2-methylsulfanyl-3,5-dihydro-imidazol-4-one 
• 6330-09-2 5-benzyl-2-thiohydantoin 
• 150-30-1 Phenylalanine 
• 27395-19-3 N-formyl-phenylalanine amide 
• 3775-01-7 5-benzylidenehydantoin 
• 51009-63-3 2-Methylsulfanyl-5-[1-phenyl-meth-(Z)-ylidene]-3,5-dihydro-imidazol-4-one 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 330591-82-7 3-Morpholin-4-ylmethyl-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-imidazolidin-4-one 
• 911371-94-3 2-(2-Bromo-ethylsulfanyl)-5-[1-phenyl-meth-(Z)-ylidene]-3,5-dihydro-imidazol-4-one 
• 911371-82-9 2-(2-Oxo-propylsulfanyl)-5-[1-phenyl-meth-(Z)-ylidene]-3,5-dihydro-imidazol-4-one 

Relevant articles and documents

Bioisosteric modification of known fucosidase inhibitors to discover a novel inhibitor of α-l-fucosidase

Bioisosteric modification of known fucosidase inhibitors A and B, resulted in three new types of molecules, 4b, 5c and 6a (belonging to furopyridinedione, thiohydantoin and hydantoin chemotypes) that could potentially bind to α-l-fucosidase (bovine kidney

Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents

Eighteen new 5-benzylidene-3-(4-arylpiperazin-1-ylmethyl)-2-thioxo-imidazolidin-4-ones were designed as hybrid structures from previously reported anticonvulsant compounds, synthesized and tested for anticonvulsant activity. Initial anticonvulsant screeni

SYNTHESIS OF IMIDAZOLE-2-THIONES VIA THIOHYDANTOINS

The present invention provides a method of making an imidazole 2-thione which comprises the step(s) of reducing a thiohydantoin to said imidazole- 2-thione.