3-(5-broMo-2-chloropyriMidin-4-yl)-1-(phenylsulfonyl)-1H-indole

Base Information

Chemical Name:3-(5-broMo-2-chloropyriMidin-4-yl)-1-(phenylsulfonyl)-1H-indole
CAS No.:1624262-44-7
Molecular Formula:C18H11BrClN3O2S
Molecular Weight:448.72084
Hs Code.:
Mol file:1624262-44-7.mol

Synonyms:3-(5-broMo-2-chloropyriMidin-4-yl)-1-(phenylsulfonyl)-1H-indole

Suppliers and Price of 3-(5-broMo-2-chloropyriMidin-4-yl)-1-(phenylsulfonyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(5-Bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole 95+%
250mg
$ 341.00

Crysdot
3-(5-Bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole 95+%
1g
$ 851.00

Chemenu
3-(5-Bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole 95%
1g
$ 804.00

Alichem
3-(5-Bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole
1g
$ 877.20

Abosyn
3-(5-Bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole 95-98%
1g
$ 800.00

Total 6 raw suppliers

Chemical Property of 3-(5-broMo-2-chloropyriMidin-4-yl)-1-(phenylsulfonyl)-1H-indole

Chemical Property:

Boiling Point:668.1±65.0 °C(Predicted)
PKA:-3.21±0.40(Predicted)
Density:1.65±0.1 g/cm3(Predicted)
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3-(5-Bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(5-broMo-2-chloropyriMidin-4-yl)-1-(phenylsulfonyl)-1H-indole

There total 3 articles about 3-(5-broMo-2-chloropyriMidin-4-yl)-1-(phenylsulfonyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1356962-87-2
3-(5-Bromo-2-chloropyrimidin-4-yl)-1H-indole

: 98-09-9
benzenesulfonyl chloride

: 1624262-44-7
3-(5-bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole

Guidance literature:: 3-(5-Bromo-2-chloropyrimidin-4-yl)-1H-indole; With sodium t-butanolate; In tetrahydrofuran; at 0 ℃; for 0.5h;

benzenesulfonyl chloride; In tetrahydrofuran; at 0 ℃; for 0.5h;

Reference yield: 39.0%

: 36082-50-5
2,4-dichloro-5-bromopyrimidine

: 129271-98-3
1-(phenylsulfonyl)-1H-indol-3-ylboronic acid

: 1624262-44-7
3-(5-bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; acetonitrile; Inert atmosphere; Reflux;
DOI:10.1021/jacs.5b07090

Reference yield:

: 120-72-9
indole

: 1624262-44-7
3-(5-bromo-2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 0.5 h / 80 °C

1.2: 18 h / 80 °C

2.1: sodium t-butanolate / tetrahydrofuran / 0.5 h / 0 °C

2.2: 0.5 h / 0 °C

With aluminum (III) chloride; sodium t-butanolate; In tetrahydrofuran; 1,2-dichloro-ethane;