129271-98-3

Basic information

• Product Name: 1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID
• Synonyms: AKOS BRN-0396;1-PHENYLSULPHONYLINDOLE-3-BORONIC ACID;1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID;1-(PHENYLSULFONYL)-3-INDOLEBORONIC ACID;1-PHENYLSULFONYLINDOLE-3-BORONIC ACID;1-(Phenylsulphonyl)-1H-indole-3-boronic acid;1-(PHENYLSULFONYL)-3-INDOLEBORONIC ACI&;1-(Phenylsulphonyl)-1H-indole-3-boronic acid 97%
• CAS NO: 129271-98-3
• Molecular Formula: C₁₄H₁₂BNO₄S
• Molecular Weight: 301.13
• Product Categories: Boronic acids;Boronic Acids;Boronic Acids and Derivatives;Heteroaryl
• Mol File: 129271-98-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 144 °C (dec.)(lit.)
• Boiling Point: 581.384 °C at 760 mmHg
• Flash Point: 305.41 °C
• Appearance: /
• Density: 1.35 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.633
• Storage Temp.: 2-8°C
• PKA: 7.98±0.30(Predicted)
• CAS DataBase Reference: 1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID(129271-98-3)
• EPA Substance Registry System: 1-(PHENYLSULFONYL)-1H-INDOL-3-YLBORONIC ACID(129271-98-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• Hazardous Substances Data: 129271-98-3(Hazardous Substances Data)

Usage

Uses

1-(Phenylsulfonyl)-3-indolylboronic acid can be used for chemoselective cross-coupling to form carbon-carbon bonds.

InChI:InChI=1/C14H12BNO4S/c17-15(18)13-10-16(14-9-5-4-8-12(13)14)21(19,20)11-6-2-1-3-7-11/h1-10,17-18H

Upstream product

• 120-72-9 indole 
• 121-43-7 Trimethyl borate 
• 99655-68-2 3-bromo-1-phenylsulfonyl indole 
• 1484-27-1 3-bromoindole 
• 98-09-9 benzenesulfonyl chloride 
• 40899-71-6 1-benzenesulfonylindole 

Downstream Products

• 944347-26-6 C₃₄H₂₄N₂O₄S₂ 
• 1031342-07-0 ethyl N-(tert-butoxycarbonyl)-4-[1-(phenylsulfonyl)-1H-indol-3-yl]-L-phenylalaninate 
• 1296269-78-7 4-(1-benzenesulfonyl-1H-indol-3-yl)-5-(methylthio)-1,3-diphenyl-1H-pyrazole 
• 1431631-59-2 C₂₀H₂₃NO₃S 
• 1431631-23-0 C₂₀H₂₁NO₃S 
• 1417986-52-7 C₅₁H₂₂BiF₁₀N₅O₂S 
• 1390666-41-7 C₃₉H₄₂N₂O₆S 
• 1350918-54-5 N-(2-(2-(dimethylamino)ethoxy)phenyl)-4-(1-(phenylsulfonyl)-1H-indol-3-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-2-carboxamide 
• 1227410-04-9 5-[1-(benzenesulfonyl)-1H-indol-3-yl]-1-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrazole-3-carboxamide 
• 1330660-67-7 (S)-3-(2-(1-(phenylsulfonyl)-1H-indol-3-yl)propanoyl)oxazolidin-2-one 
• 1313585-72-6 C₃₈H₃₃F₁₇N₂O₅S 

Relevant articles and documents

FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS

The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a proliferative disease, preferably cancer, using compounds of the invention.

HETEROARYL SUBSTITUTED PHENYL ISOXAZOLE SULFONAMIDE ENDOTHELIN ANTAGONISTS

Compounds of the formula STR1 inhibit the activity of endothelin.