METHYL 2,4-DIHYDROXY-3-NITROBENZOATE

Base Information

• Chemical Name: METHYL 2,4-DIHYDROXY-3-NITROBENZOATE
• CAS No.: 956105-56-9
• Molecular Formula: C8H7NO6
• Molecular Weight: 213.147
• Hs Code.: 2918199090
• Mol file: 956105-56-9.mol

Synonyms:METHYL 2,4-DIHYDROXY-3-NITROBENZOATE;2,4-Dihydroxy-3-nitro-benzoic acid methyl ester

Chemical Property of METHYL 2,4-DIHYDROXY-3-NITROBENZOATE

Chemical Property:

• PSA: 112.58000
• LogP: 1.31580

Purity/Quality:

98% ^*data from raw suppliers

methyl2,4-dihydroxy-3-nitrobenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 2,4-DIHYDROXY-3-NITROBENZOATE

There total 2 articles about METHYL 2,4-DIHYDROXY-3-NITROBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

methyl 2,4-dihydroxybenzoate (2150-47-2) → 2,4-dihydroxy-3-nitrobenzoic acid methyl ester (956105-56-9) + 2,4-dihydroxy-5-nitro-benzoic acid methyl ester (271261-71-3)

Guidance literature:

With nitric acid; acetic anhydride; In acetic acid; at 0 - 22 ℃;

DOI:10.1055/s-2007-983843

Reference yield: 25.0%

methyl 2,4-dihydroxybenzoate (2150-47-2) → 2,4-dihydroxy-3-nitrobenzoic acid methyl ester (956105-56-9)

Guidance literature:

With nitric acid; acetic acid; at 0 - 20 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1039/c3ob41975d

Reference yield: 98.0%

2,4-dihydroxy-3-nitrobenzoic acid methyl ester (956105-56-9) + chloromethyl methyl ether (107-30-2) → methyl 2,4-bis(methoxymethoxy)-3-nitrobenzoate (956105-76-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; sodium iodide; In 1,2-dimethoxyethane; N,N-dimethyl-formamide; at 55 ℃; for 1h;

DOI:10.1055/s-2007-983843

upstream raw materials:

methyl 2,4-dihydroxybenzoate

Downstream raw materials:

methyl 2,4-bis(methoxymethoxy)-3-nitrobenzoate

methyl 3-amino-2,4-bis(methoxymethoxy)benzoate

2-(trimethylsilyl)-ethyl 2,4-dihydroxy-3-nitrobenzoate

2,4-bis-benzyloxy-3-nitrobenzoic acid methyl ester