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Benzoic acid, 2,4-dihydroxy-5-nitro-, methyl ester (9CI) is a chemical compound characterized by the molecular formula C8H7NO5. It is a derivative of benzoic acid with a methyl ester group and possesses a nitro and two hydroxyl groups at the 5th and 2nd/4th positions, respectively. Benzoic acid, 2,4-dihydroxy-5-nitro-, methyl ester (9CI) is recognized for its potential mutagenicity, cytotoxic, antimicrobial, antioxidant, and anti-inflammatory properties, making it a versatile chemical intermediate in the synthesis of pharmaceuticals, dyes, and fragrances.

271261-71-3

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271261-71-3 Usage

Uses

Used in Pharmaceutical Industry:
Benzoic acid, 2,4-dihydroxy-5-nitro-, methyl ester (9CI) is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its cytotoxic properties make it a candidate for the development of anticancer drugs, targeting cancer cells and inhibiting their growth. Additionally, its antimicrobial properties can be utilized in the formulation of antimicrobial agents to combat bacterial infections.
Used in Dye and Fragrance Industry:
In the dye and fragrance industry, Benzoic acid, 2,4-dihydroxy-5-nitro-, methyl ester (9CI) is used as a key intermediate in the production of various dyes and fragrances. Its unique chemical structure contributes to the color and scent profiles of these products, enhancing their performance and appeal.
Used in Antioxidant and Anti-inflammatory Applications:
Benzoic acid, 2,4-dihydroxy-5-nitro-, methyl ester (9CI) exhibits antioxidant and anti-inflammatory effects, making it a potential candidate for therapeutic applications in conditions such as cancer and inflammation. Its antioxidant properties can help neutralize harmful free radicals, while its anti-inflammatory effects can alleviate inflammation and reduce associated symptoms.
However, it is important to note that the toxicity and potential health hazards of Benzoic acid, 2,4-dihydroxy-5-nitro-, methyl ester (9CI) should be carefully considered and further studied before any widespread applications. Its mutagenicity and cytotoxic properties may pose risks to human health and the environment, necessitating thorough research and safety assessments.

Check Digit Verification of cas no

The CAS Registry Mumber 271261-71-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,1,2,6 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 271261-71:
(8*2)+(7*7)+(6*1)+(5*2)+(4*6)+(3*1)+(2*7)+(1*1)=123
123 % 10 = 3
So 271261-71-3 is a valid CAS Registry Number.

271261-71-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 2,4-dihydroxy-5-nitrobenzoate

1.2 Other means of identification

Product number -
Other names BENZOIC ACID,2,4-DIHYDROXY-5-NITRO-,METHYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:271261-71-3 SDS

271261-71-3Relevant academic research and scientific papers

An efficient entry to amino-substituted resorcylic acid derivatives for the synthesis of platensimycin and analogues

Heretsch, Philipp,Giannis, Athanassios

, p. 2614 - 2616 (2007)

An efficient entry to protected amino-substituted resorcylic acid derivatives, methyl 3- or 5-amino-2,4-bis(methoxymethoxy)benzoate, is reported. Both derivatives can be used for the synthesis of platensimycin and its analogues. Georg Thieme Verlag Stuttg

Multiturn Hollow Helices: Synthesis and Folding of Long Aromatic Oligoamides

Ferrand, Yann,Gong, Bing,Huc, Ivan,Kauffmann, Brice,Liu, Rui,Lu, Zhong-Lin,Xu, Wenwu,Zeng, Xiao Cheng,Zhong, Yulong

, p. 6938 - 6942 (2020/09/15)

Aromatic oligoamides adopting helical conformations are synthesized by coupling carboxyl-terminated basic units having two, four, and eight residues to amine-terminated oligomer precursors. Coupling yields show no noticeable reduction with the size of the

IMMUNOMODULATORS, COMPOSITIONS AND METHODS THERE OF

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Page/Page column 29, (2020/05/06)

Provided herein is compounds of Formula I, methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer

IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF

-

Page/Page column 42-43, (2020/08/22)

Provided herein are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.

CAVITY-CONTAINING OLIGOMERS AND POLYMERS EFFECTIVE IN CRYOPRESERVATION

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Paragraph 0033; 0116, (2019/06/09)

The present invention provides compositions and methods for cryopreservation utilizing aromatic cavity-containing oligomers and polymers that contain structural motifs capable of shape-inducing intramolecular bonding to form cavities. The cavity-containin

HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS

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Page/Page column 87-88, (2017/06/12)

Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or

Synthesis of crescent aromatic oligoamides

Yuan, Lihua,Sanford, Adam R.,Feng, Wen,Zhang, Aimin,Zhu, Jin,Zeng, Huaqiang,Yamato, Kazuhiro,Li, Minfeng,Ferguson, Joseph S.,Gong, Bing

, p. 10660 - 10669 (2007/10/03)

This article describes the synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in recent years in our laboratory. The large-scale preparation of a variety of monomers derived from various tetrasubstituted benzenes is presented. Three different strategies for constructing various oligomers consisting of meta- and meta/para-linked benzene residues are discussed. Factors affecting coupling efficiency and yields are analyzed. The developed synthetic methods have provided the basis for the preparation of longer oligomers and for the development of solid-phase synthesis.

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