271261-71-3Relevant academic research and scientific papers
An efficient entry to amino-substituted resorcylic acid derivatives for the synthesis of platensimycin and analogues
Heretsch, Philipp,Giannis, Athanassios
, p. 2614 - 2616 (2007)
An efficient entry to protected amino-substituted resorcylic acid derivatives, methyl 3- or 5-amino-2,4-bis(methoxymethoxy)benzoate, is reported. Both derivatives can be used for the synthesis of platensimycin and its analogues. Georg Thieme Verlag Stuttg
Multiturn Hollow Helices: Synthesis and Folding of Long Aromatic Oligoamides
Ferrand, Yann,Gong, Bing,Huc, Ivan,Kauffmann, Brice,Liu, Rui,Lu, Zhong-Lin,Xu, Wenwu,Zeng, Xiao Cheng,Zhong, Yulong
, p. 6938 - 6942 (2020/09/15)
Aromatic oligoamides adopting helical conformations are synthesized by coupling carboxyl-terminated basic units having two, four, and eight residues to amine-terminated oligomer precursors. Coupling yields show no noticeable reduction with the size of the
IMMUNOMODULATORS, COMPOSITIONS AND METHODS THERE OF
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Page/Page column 29, (2020/05/06)
Provided herein is compounds of Formula I, methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer
IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF
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Page/Page column 42-43, (2020/08/22)
Provided herein are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.
CAVITY-CONTAINING OLIGOMERS AND POLYMERS EFFECTIVE IN CRYOPRESERVATION
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Paragraph 0033; 0116, (2019/06/09)
The present invention provides compositions and methods for cryopreservation utilizing aromatic cavity-containing oligomers and polymers that contain structural motifs capable of shape-inducing intramolecular bonding to form cavities. The cavity-containin
HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
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Page/Page column 87-88, (2017/06/12)
Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or
Synthesis of crescent aromatic oligoamides
Yuan, Lihua,Sanford, Adam R.,Feng, Wen,Zhang, Aimin,Zhu, Jin,Zeng, Huaqiang,Yamato, Kazuhiro,Li, Minfeng,Ferguson, Joseph S.,Gong, Bing
, p. 10660 - 10669 (2007/10/03)
This article describes the synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in recent years in our laboratory. The large-scale preparation of a variety of monomers derived from various tetrasubstituted benzenes is presented. Three different strategies for constructing various oligomers consisting of meta- and meta/para-linked benzene residues are discussed. Factors affecting coupling efficiency and yields are analyzed. The developed synthetic methods have provided the basis for the preparation of longer oligomers and for the development of solid-phase synthesis.
