N,N-dimethyl-1-(naphthalen-1-yl)methanamine

Base Information

• Chemical Name: N,N-dimethyl-1-(naphthalen-1-yl)methanamine
• CAS No.: 16413-71-1
• Molecular Formula: C13H15 N
• Molecular Weight: 185.269
• Hs Code.: 2921490090
• NSC Number: 100674
• DSSTox Substance ID: DTXSID50295222
• Nikkaji Number: J793.822E
• Wikidata: Q82035021
• ChEMBL ID: CHEMBL168577
• Mol file: 16413-71-1.mol

Synonyms:16413-71-1;N,N-dimethyl-1-(naphthalen-1-yl)methanamine;1-naphthalenemethanamine, n,n-dimethyl-;N,N-dimethyl-1-naphthalen-1-ylmethanamine;CHEMBL168577;NSC100674;1-Naphthylmethyldimethylamine;NCIOpen2_002147;SCHEMBL820553;DTXSID50295222;Dimethyl-naphthalen-1-ylmethyl-amine;N,N-dimethyl(1-naphthyl)methanamine;BDBM50016924;MFCD05124184;AKOS003962561;1-(N,N-dimethylaminomethyl)naphthalene;dimethyl[(naphthalen-1-yl)methyl]amine;NSC 100674;NSC-100674;DS-13355;N,N-dimethyl(naphthalene-1-yl)methanamine;C73168

Chemical Property of N,N-dimethyl-1-(naphthalen-1-yl)methanamine

Chemical Property:

• Vapor Pressure: 0.0046mmHg at 25°C
• Boiling Point: 277.2°Cat760mmHg
• PKA: 8?+-.0.28(Predicted)
• Flash Point: 111°C
• PSA: 3.24000
• Density: 1.028g/cm³
• LogP: 2.90140
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 185.120449483
• Heavy Atom Count: 14
• Complexity: 176

Purity/Quality:

N,N-Dimethyl-1-(naphthalen-1-yl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC1=CC=CC2=CC=CC=C21
• Uses: N,N-Dimethyl-1-(naphthalen-1-yl)methanamine is a useful reactant in organic synthesis.

Technology Process of N,N-dimethyl-1-(naphthalen-1-yl)methanamine

There total 27 articles about N,N-dimethyl-1-(naphthalen-1-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-methyl-1-naphthalenemethylamine (14489-75-9) → N,N-dimethyl(naphthalen-1-yl)methanamine (16413-71-1)

Guidance literature:

With sodium dihydrogen phosphate; In 1,4-dioxane; water; at 60 ℃; for 0.166667h;

DOI:10.1016/S0040-4039(01)81224-7

Reference yield: 95.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 1-Chloromethylnaphthalene (86-52-2) → N,N-dimethyl(naphthalen-1-yl)methanamine (16413-71-1)

Guidance literature:

With NHC-Pd(II)-Im; sodium hydroxide; In water; at 50 ℃; for 3h; Inert atmosphere; Schlenk technique;

DOI:10.3184/174751913X13787959859344

Reference yield: 92.0%

N,N-dimethylammonium chloride (506-59-2) + 1-naphthaldehyde (66-77-3) → N,N-dimethyl(naphthalen-1-yl)methanamine (16413-71-1)

Guidance literature:

N,N-dimethylammonium chloride; 1-naphthaldehyde; With sodium acetate; sodium tris(acetoxy)borohydride; acetic acid; In tetrahydrofuran; for 12h;

With sodium hydrogencarbonate; In dichloromethane; water;

upstream raw materials:

N-methyl-1-naphthalenemethylamine

formaldehyd

N,N-dimethyl(methylene)ammonium chloride

1-(tributylstannyl)naphthalene

Downstream raw materials:

Dimethyl-naphthalen-1-ylmethyl-phenoxymethyl-ammonium; chloride

(8-dimethylaminomethyl)naphthylphenyldifluorosilane

NCNMe₂

3-Phenyl-1H,3H-benzo[de]isochromen-1-one