2-(chloroMethyl)-3,5-difluoropyridine

Base Information

Chemical Name:2-(chloroMethyl)-3,5-difluoropyridine
CAS No.:1222633-85-3
Molecular Formula:C6H4ClF2N
Molecular Weight:163.5524664
Hs Code.:
Mol file:1222633-85-3.mol

Synonyms:2-(chloroMethyl)-3,5-difluoropyridine

Suppliers and Price of 2-(chloroMethyl)-3,5-difluoropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloromethyl-3,5-difluoropyridine 95%+
1g
$ 1381.00

Crysdot
2-(Chloromethyl)-3,5-difluoropyridine 95+%
1g
$ 672.00

Chemenu
2-(Chloromethyl)-3,5-difluoropyridine 95%
1g
$ 635.00

American Custom Chemicals Corporation
2-(CHLOROMETHYL)-3,5-DIFLUOROPYRIDINE 95.00%
5MG
$ 502.25

Acints
2-Chloromethyl-3,5-difluoro-pyridine 95%+
5g
$ 2167.75

Acints
2-Chloromethyl-3,5-difluoro-pyridine 95%+
1g
$ 674.25

Total 15 raw suppliers

Chemical Property of 2-(chloroMethyl)-3,5-difluoropyridine

Chemical Property:

Boiling Point:158.2±35.0 °C(Predicted)
PKA:-1.15±0.32(Predicted)
PSA：12.89000
Density:1.377±0.06 g/cm3(Predicted)
LogP:2.09860
Storage Temp.:2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloromethyl-3,5-difluoropyridine 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(chloroMethyl)-3,5-difluoropyridine

There total 7 articles about 2-(chloroMethyl)-3,5-difluoropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1065267-14-2
(3,5-difluoro-pyridin-2-yl)-methanol

: 1222633-85-3
2-(chloromethyl)-3,5-difluoropyridine

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h; Cooling with ice;

Reference yield:

: 745784-04-7
3,5-difluoropyridine-2-carboxylic acid

: 1222633-85-3
2-(chloromethyl)-3,5-difluoropyridine

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 3 h / 60 °C / Cooling with ice

2: sodium tetrahydroborate / ethanol / 2 h / 0 - 20 °C / Cooling with ice

3: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C / Cooling with ice

With sodium tetrahydroborate; thionyl chloride; N,N-dimethyl-formamide; In ethanol; dichloromethane;

Reference yield:

: 1065267-10-8
3,5-difluoro-pyridine-2-carboxylic acid ethyl ester

: 1222633-85-3
2-(chloromethyl)-3,5-difluoropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol / 2 h / 0 - 20 °C / Cooling with ice

2: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C / Cooling with ice

With sodium tetrahydroborate; thionyl chloride; N,N-dimethyl-formamide; In ethanol; dichloromethane;