1065267-14-2

Basic information

• Product Name: (3,5-difluoropyridin-2-yl)Methanol
• Synonyms: (3,5-difluoropyridin-2-yl)Methanol;2-Pyridinemethanol, 3,5-difluoro-
• CAS NO: 1065267-14-2
• Molecular Formula: C₆H₅F₂NO
• Molecular Weight: 145.1068064
• Mol File: 1065267-14-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 176.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.383±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.34±0.10(Predicted)
• CAS DataBase Reference: (3,5-difluoropyridin-2-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-difluoropyridin-2-yl)Methanol(1065267-14-2)
• EPA Substance Registry System: (3,5-difluoropyridin-2-yl)Methanol(1065267-14-2)

Safety Data

• Hazardous Substances Data: 1065267-14-2(Hazardous Substances Data)

Usage

General Description

(3,5-difluoropyridin-2-yl)Methanol is a chemical compound with the molecular formula C6H5F2NO. It is a derivative of pyridine, which is a six-membered heterocyclic ring containing five carbon atoms and one nitrogen atom. The presence of two fluorine atoms on the 3rd and 5th positions of the pyridine ring gives this compound its unique properties. (3,5-difluoropyridin-2-yl)Methanol is used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in the production of specialty chemicals and materials. The presence of the methanol group in this compound allows for various chemical reactions and functionalizations, making it a versatile building block in organic synthesis.

Upstream product

• 1033202-51-5 5-fluoro-3-nitropyridine-2-carbonitrile 
• 1052714-11-0 3-amino-5-fluoropyridine-2-carboxylic acid methyl ester 
• 1374115-60-2 3-amino-5-fluoropicolinonitrile 
• 298709-29-2 3,5-difluoropyridine-2-carbonitrile 
• 955885-64-0 methyl 3,5-difluoropyridine-2-carboxylate 
• 745784-04-7 3,5-difluoropyridine-2-carboxylic acid 
• 1065267-10-8 3,5-difluoro-pyridine-2-carboxylic acid ethyl ester 

Downstream Products

• 780801-58-3 3,5-difluoropicolinaldehyde 
• 1442451-89-9 5-chloro-6-((3,5-difluoropyridin-2-yl)methoxy)-3-(5-(2-(2-hydroxypropan-2-yl)pyrimidin-4-yl)-2-methylphenyl)-2-methylpyrimidin-4(3H)-one 
• 1222633-85-3 2-(chloromethyl)-3,5-difluoropyridine 
• 1428987-10-3 (3,5-Difluoropyridin-2-yl)methyl 4-methylbenzenesulfonate 

Relevant articles and documents

PROCESS, COMPOSITIONS, AND CRYSTALLINE FORMS OF SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

The present disclosure provides a crystalline form of the methyl/fluoro-pyridinyl-methoxy substituted pyridinone-pyridinyl compound of the structure: XRPD, TGA, and DSC data on the crystalline form, as well as methods preparing the crystalline form, inclu

PYRIDO[2,3-d]PYRIMIDIN-4-ONE COMPOUNDS AS TANKYRASE INHIBITORS

Pyrido[2,3-d]pyrimidin-4-one compounds, formulations containing those compounds, and their use as tankyrase 1 and 2 inhibitors Formula (I).

3 -AMINO- PYRAZOLE DERIVATIVES USEFUL AGAINST TUBERCULOSIS

A compound of Formula (I) or a pharmaceutically acceptable salt thereof: Wherein: Het is a 5 to 10-membered heteroaromatic ring; Either X is N and Y is CR5; or X is C and Y is S; Z is selected from N and CH; R1 is selected from H and C1-2alkyl; R2 is selected from H, C1-2alkyl, OH, —CH2OH and C1-2alkoxy; Each R3 is independently selected from OH, C1-3alkyl, F, Cl, Br, NH2, and C1-3alkoxy; R4 is selected from C1-3alkyl and haloC1-3alkyl; R5 is selected from H, C1-3alkyl and haloC1-3alkyl; R6 and R7 are either i) each independently selected from H, C1-3alkyl and C1-3alkoxy; or ii) R6 and R7 together with the ring to which they are attached form a 9-membered bicyclic ring; p is 0-3; and RA is selected from H and C1-3alkyl, compositions containing them, their use in therapy, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.