745784-04-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3,5-Difluoropicolinic acid is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals for its ability to contribute to the development of novel compounds with enhanced biological activities.
Used in Research and Development:
In the field of research and development, 3,5-Difluoropicolinic acid serves as a building block for the creation of new chemical compounds, leveraging its unique structure to explore potential applications in biological and medicinal chemistry.
Used in Drug Discovery and Chemical Biology:
3,5-Difluoropicolinic acid is utilized as a valuable tool in drug discovery and chemical biology, where the presence of fluorine atoms can alter the physicochemical properties and pharmacokinetics of molecules, leading to the discovery of improved drug candidates with optimized performance in biological systems.

InChI:InChI=1/C6H3F2NO2/c7-3-1-4(8)5(6(10)11)9-2-3/h1-2H,(H,10,11)

Upstream product

• 298709-29-2 3,5-difluoropyridine-2-carbonitrile 

Downstream Products

• 943636-84-8 C₂₇H₂₉F₂N₅O₄ 
• 1046858-35-8 4-(2,4-dichlorophenyl)-6-[(3,5-difluoropyridin-2-yl)carbonyl]-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-amine 
• 955885-64-0 methyl 3,5-difluoropyridine-2-carboxylate 
• 1427468-57-2 3-(3-bromophenyl)-6-(3,5-difluoropyridin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1427468-62-9 3-(4-bromophenyl)-6-(3,5-difluoropyridin-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1427468-68-5 3-(2-chlorophenyl)-6-(3,5-difluoropyridin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1575754-67-4 C₁₂H₈F₂N₂O 
• 1575753-60-4 C₁₆H₁₅F₂N₃O₂ 
• 1105511-51-0 (2R,6S)-4-(2-((tert-butyldiphenylsilyloxy)methyl)-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine 
• 1105510-17-5 (2R,6S)-4-(2-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine 
• 1105510-20-0 (2R,6S)-4-(6-bromo-2-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine 
• 1256836-96-0 methyl 3-fluoro-5-hydroxypyridine-2-carboxylate 
• 745784-03-6 3,5-difluoropyridine amide 

Relevant academic research and scientific papers

SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING ?-SECRETASE-INHIBITING ACTIVITY

The following compound is provided as an agent for treating a disease induced by production, secretion and/or deposition of amyloid β protein, for example,. a compound represented by the formula (I): wherein ruing A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group, R1 is optionally substituted lower alkyl or the like, R2a and R2b are each independently hydrogen, optionally substituted lower alkyl or the like, R3a and R3c are each independently hydrogen, halogen, hydroxy, optionally substituted lower alkyl or the like, or a pharmaceutically acceptable salt thereof, or a solvate thereof.