4,6-Dichloropyridine-2-carbonitrile

Base Information

Chemical Name:4,6-Dichloropyridine-2-carbonitrile
CAS No.:40314-71-4
Molecular Formula:C6H2Cl2N2
Molecular Weight:173.001
Hs Code.:2933399990
European Community (EC) Number:813-190-2
Mol file:40314-71-4.mol

Synonyms:4,6-Dichloropicolinonitrile;40314-71-4;4,6-dichloropyridine-2-carbonitrile;MFCD22684690;SCHEMBL7052498;AMY10090;AKOS027324613;CS-W023128;SB52796;AS-47055;SY059543;F11780;EN300-7232091;A914131;Z1618031302

Suppliers and Price of 4,6-Dichloropyridine-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,6-Dichloropyridine-2-carbonitrile
100mg
$ 90.00

SynQuest Laboratories
4,6-Dichloropyridine-2-carbonitrile 98%
1 g
$ 440.00

Matrix Scientific
4,6-Dichloropicolinonitrile 97%
10g
$ 650.00

Matrix Scientific
4,6-Dichloropicolinonitrile 97%
25g
$ 1295.00

Crysdot
4,6-Dichloropicolinonitrile 95+%
5g
$ 662.00

Apolloscientific
4,6-Dichloropyridine-2-carbonitrile 98%
1g
$ 275.00

Alichem
4,6-Dichloropicolinonitrile
1g
$ 2981.85

Alichem
4,6-Dichloropicolinonitrile
250mg
$ 989.80

Total 11 raw suppliers

Chemical Property of 4,6-Dichloropyridine-2-carbonitrile

Chemical Property:

Boiling Point:251.1±35.0 °C(Predicted)
PKA:-5.80±0.10(Predicted)
PSA：36.68000
Density:1.49±0.1 g/cm3(Predicted)
LogP:2.26008
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:171.9595035
Heavy Atom Count:10
Complexity:162

Purity/Quality:

97% ^*data from raw suppliers

4,6-Dichloropyridine-2-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(N=C1C#N)Cl)Cl

Technology Process of 4,6-Dichloropyridine-2-carbonitrile

There total 2 articles about 4,6-Dichloropyridine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 13602-59-0
2,4-dichloropyridine-N-oxide

: 7677-24-9
trimethylsilyl cyanide

: 40314-71-4
4,6-dichloropyridine-2-carbonitrile

Guidance literature:: With triethylamine; In acetonitrile; for 2h; Inert atmosphere; Reflux;
DOI:10.1021/ml500066m

Reference yield:

: 26452-80-2
2,4-dichloropyridine

: 40314-71-4
4,6-dichloropyridine-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12.5 h / 5 - 25 °C

2: triethylamine / acetonitrile / 12 h / 80 °C

With triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetonitrile;

Reference yield: 83.0%

: 40314-71-4
4,6-dichloropyridine-2-carbonitrile

: 399-96-2
4-amino-2-fluorophenol

: 1584220-31-4
4-(4-amino-2-fluorophenoxy)-6-chloropicolinonitrile

Guidance literature:: 4-amino-2-fluorophenol; With potassium tert-butylate; In N,N-dimethyl acetamide; at 20 ℃; for 0.5h; Inert atmosphere;

4,6-dichloropyridine-2-carbonitrile; In N,N-dimethyl acetamide; at 80 ℃; for 4h; Inert atmosphere;
DOI:10.1021/ml500066m