TriMethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- Mixture)

Base Information

• Chemical Name: TriMethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- Mixture)
• CAS No.: 185855-30-5
• Molecular Weight: 258.27
• Mol file: 185855-30-5.mol

Synonyms:TriMethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- Mixture);Trimethyl 1,2,4-Cyclohexanetricarboxylate;Trimethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- mixture)

Chemical Property of TriMethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- Mixture)

Chemical Property:

• Refractive Index: 1.4660 to 1.4700

Purity/Quality:

98%,99%, ^*data from raw suppliers

Trimethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- mixture) >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TriMethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- Mixture)

There total 39 articles about TriMethyl 1,2,4-Cyclohexanetricarboxylate (cis- and trans- Mixture) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

trimethyl cyclohex-5-ene-1,2,4-tricarboxylate (1257982-53-8) → 1,2,4-cyclohexanetricarboxylic acid trimethyl ester (185855-30-5)

Guidance literature:

With hydrogen; 5% Pd(II)/C(eggshell); In dichloromethane; for 2h;

Reference yield:

trimethyl cyclohex-5-ene-1,2,4-tricarboxylate (1257982-53-8) → benzene-1,2,4-tricarboxylic acid trimethyl ester (2459-10-1) + 1,2,4-cyclohexanetricarboxylic acid trimethyl ester (185855-30-5)

Guidance literature:

5% Pd(II)/C(eggshell); In diethylene glycol dimethyl ether; for 27h; Reflux; Inert atmosphere;

Reference yield:

methanol (67-56-1) + cyclohexane-1,2,4-tricarboxylic acid 1,2-anhydride (53611-01-1) → (1S,2S,4S)-cyclohexane-1,2,4-tricarboxylic acid-1,2-anhydride-4-methyl ester + (1R,2S,4S)-cyclohexane-1,2,4-tricarboxylic acid-1,2-anhydride-4-ethyl mester + 1,2,4-cyclohexanetricarboxylic acid trimethyl ester (185855-30-5)

Guidance literature:

In o-xylene; at 180 - 235 ℃; for 13h;

upstream raw materials:

methanol

cyclohexane-1,2,4-tricarboxylic acid 1,2-anhydride

trimethyl cyclohex-5-ene-1,2,4-tricarboxylate

diazomethane

Refernces

• 1、 -. "Acid anhydride ester and composition thereof, and heat-curable resin composition and cured product thereof". Page/Page column 10-11. . Retrieved 2008/06/13.
• 2、 Isoda,Yamaguchi. "Medicinal chemical studies on antiplasmin drugs. VIII. 4-aminomethylcyclohexanecarboxylic acid derivatives having a carboxyl or carboxymethyl group at C2". . p. 2337 - 2346. Retrieved 2007/10/02.