BIA10-2474

Base Information

Chemical Name:BIA10-2474
CAS No.:1233855-46-3
Molecular Formula:C16H20N4O2
Molecular Weight:300.36
Hs Code.:
Mol file:1233855-46-3.mol

Synonyms:BIA10-2474

Suppliers and Price of BIA10-2474

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Cyclohexyl-N-methyl-4-(1-oxido-3-pyridinyl)-1H-imidazole-1-carboxamide
25mg
$ 345.00

DC Chemicals
BIA10-2474 >98%
1 g
$ 2100.00

DC Chemicals
BIA10-2474 >98%
100 mg
$ 600.00

Crysdot
BIA10-2474 98+%
25mg
$ 183.00

Crysdot
BIA10-2474 98+%
5mg
$ 74.00

Crysdot
BIA10-2474 98+%
100mg
$ 381.00

ChemScene
BIA10-2474 98.41%
100mg
$ 580.00

ChemScene
BIA10-2474 98.41%
50mg
$ 375.00

ChemScene
BIA10-2474 98.41%
5mg
$ 60.00

ChemScene
BIA10-2474 98.41%
10mg
$ 105.00

Total 12 raw suppliers

Chemical Property of BIA10-2474

Chemical Property:

PSA：63.59000
LogP:3.21120

Purity/Quality:

99%, ^*data from raw suppliers

N-Cyclohexyl-N-methyl-4-(1-oxido-3-pyridinyl)-1H-imidazole-1-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses N-Cyclohexyl-N-methyl-4-(1-oxido-3-pyridinyl)-1H-imidazole-1-carboxamide is a potential fatty acid amide hydrolase (FAAH) inhibitor used for treating and preventing diseases.

Technology Process of BIA10-2474

There total 12 articles about BIA10-2474 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1233855-18-9
N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide

: 1233855-46-3
3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide

Guidance literature:: N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide; With peracetic acid; In dichloromethane; at 25 ℃;

With sodium metabisulfite; In dichloromethane; water; at 30 ℃; Product distribution / selectivity;

Reference yield:

: 51746-85-1
3-(1H-imidazol-4-yl)pyridine

: 1233855-46-3
3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / tetrahydrofuran / 2 - 2.5 h / 25 °C

2.1: tetrahydrofuran / 19.5 h / 25 °C

3.1: peracetic acid / dichloromethane / 25 °C

3.2: 30 °C

With pyridine; peracetic acid; In tetrahydrofuran; dichloromethane;

Reference yield:

: 5973-83-1
1-(pyridin-3-yl)ethan-1-one oxime

: 1233855-46-3
3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridine / 5 - 25 °C

1.2: 10 - 25 °C

1.3: 3 h / 80 °C

2.1: water / 15 - 90 °C

3.1: sodium nitrite; nitric acid / water / 5 - 35 °C

4.1: pyridine / dichloromethane / 25 - 90 °C

5.1: peracetic acid / dichloromethane / 20 h / 25 °C

With pyridine; peracetic acid; nitric acid; sodium nitrite; In dichloromethane; water; 1.1: |Neber Rearrangement / 1.2: |Neber Rearrangement;