1233855-18-9

Basic information

• Product Name: N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide
• Synonyms: N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide
• CAS NO: 1233855-18-9
• Molecular Weight: 284.361
• Mol File: 1233855-18-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide(1233855-18-9)
• EPA Substance Registry System: N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide(1233855-18-9)

Safety Data

• Hazardous Substances Data: 1233855-18-9(Hazardous Substances Data)

Upstream product

• 93103-29-8 4-(pyridin-3-yl)-1H-imidazole-2(3H)-thione 
• 51746-85-1 3-(1H-imidazol-4-yl)pyridine 
• 35028-38-7 N-methyl-N-cyclohexylaminocarbonyl chloride 
• 100-60-7 N-methylcyclohexylamine 
• 350-03-8 methyl-3-pyridylketone 
• 5973-83-1 1-(pyridin-3-yl)ethan-1-one oxime 
• 74209-51-1 1-pyridin-3-yl-ethanone oxime O-tosylate 
• 51746-82-8 2-amino-1-pyridin-3-yl-ethanone dihydrochloride salt 
• 1356960-88-7 C₁₅H₁₁N₃O₂ 
• 1356960-89-8 4-nitrophenyl 4-(pyridin-3-yl)-1H-imidazole-1-carboxylate 

Downstream Products

• 1233855-46-3 3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide 

Relevant articles and documents

PROCESSES FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS

The present invention concerns a process for preparing a compound having the Formula A; or a pharmaceutically acceptable salt or derivative thereof, or for preparing a substituted urea compound of Formula IIa, or a pharmaceutically acceptable salt or ester thereof, (Formula IIa) the process comprising the reaction of an imidazolyl intermediate of Formula IIa', with a carbamoyl halide of the formula: R1R2NC(=O)Hal, wherein Hal represents Cl, F, I or Br, wherein the intermediate of Formula IIa' is prepared by oxidation of the derivative of R5 and R6, R6-C(=O)CH2R5 to form a glyoxal intermediate R6-C(=O)(C=O)R5, which is subjected to treatment with ammonium hydroxide and an aldehyde R8CHO to provide the intermediate of Formula IIa', and wherein the compound substituents are as defined herein.

PROCESS FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS

A process for preparing a substitute urea of Formula (II) or Formula (I), or a pharmaceutically acceptable salt or ester thereof, Formula (II): Formula (I): the process comprising the reaction of a carbamate of Formula (II'): or formula (I'): with a prima